Modification of porous polyethylene scaffolds for cell attachment and proliferation

Poulomi Sengupta, Sachin S Surwase, Bhagavatula LV Prasad Physical Chemistry Division, CSIR–National Chemical Laboratory, Pune, India Abstract: Synthetic polymers are widely researched for their use in tissue engineering. Control in size, surface area, pore size, and elasticity are the b...

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Autores principales:	Sengupta P, Surwase SS, Prasad BLV
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Tissue engineering Gold nanoparticle HDPE Hydrophilicity Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/972e07b86ac84dc8b3f21ef19ad63031
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id	oai:doaj.org-article:972e07b86ac84dc8b3f21ef19ad63031
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spelling	oai:doaj.org-article:972e07b86ac84dc8b3f21ef19ad630312021-12-02T03:08:51ZModification of porous polyethylene scaffolds for cell attachment and proliferation1178-2013https://doaj.org/article/972e07b86ac84dc8b3f21ef19ad630312018-03-01T00:00:00Zhttps://www.dovepress.com/modification-of-porous-polyethylene-scaffolds-for-cell-attachment-and--peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Poulomi Sengupta, Sachin S Surwase, Bhagavatula LV Prasad Physical Chemistry Division, CSIR–National Chemical Laboratory, Pune, India Abstract: Synthetic polymers are widely researched for their use in tissue engineering. Control in size, surface area, pore size, and elasticity are the biggest advantages of using a man-made polymer. However, often the polymers are hydrophobic (do not encourage cell attachment); hence, it is hugely challenging to integrate them with the normal tissues. Herein, we have tried to overcome this disadvantage of polymers by coating them with citrate-stabilized gold nanoparticles and arginine. High-density polyethylene, upon multiple treatments, shows low water contact angle, which encourages cell attachment and proliferation in comparison to the untreated polymers. Keywords: tissue engineering, gold nanoparticle, HDPE hydrophilicitySengupta PSurwase SSPrasad BLVDove Medical PressarticleTissue engineeringGold nanoparticleHDPE HydrophilicityMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 13, Pp 87-90 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Tissue engineering Gold nanoparticle HDPE Hydrophilicity Medicine (General) R5-920
spellingShingle	Tissue engineering Gold nanoparticle HDPE Hydrophilicity Medicine (General) R5-920 Sengupta P Surwase SS Prasad BLV Modification of porous polyethylene scaffolds for cell attachment and proliferation
description	Poulomi Sengupta, Sachin S Surwase, Bhagavatula LV Prasad Physical Chemistry Division, CSIR–National Chemical Laboratory, Pune, India Abstract: Synthetic polymers are widely researched for their use in tissue engineering. Control in size, surface area, pore size, and elasticity are the biggest advantages of using a man-made polymer. However, often the polymers are hydrophobic (do not encourage cell attachment); hence, it is hugely challenging to integrate them with the normal tissues. Herein, we have tried to overcome this disadvantage of polymers by coating them with citrate-stabilized gold nanoparticles and arginine. High-density polyethylene, upon multiple treatments, shows low water contact angle, which encourages cell attachment and proliferation in comparison to the untreated polymers. Keywords: tissue engineering, gold nanoparticle, HDPE hydrophilicity
format	article
author	Sengupta P Surwase SS Prasad BLV
author_facet	Sengupta P Surwase SS Prasad BLV
author_sort	Sengupta P
title	Modification of porous polyethylene scaffolds for cell attachment and proliferation
title_short	Modification of porous polyethylene scaffolds for cell attachment and proliferation
title_full	Modification of porous polyethylene scaffolds for cell attachment and proliferation
title_fullStr	Modification of porous polyethylene scaffolds for cell attachment and proliferation
title_full_unstemmed	Modification of porous polyethylene scaffolds for cell attachment and proliferation
title_sort	modification of porous polyethylene scaffolds for cell attachment and proliferation
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/972e07b86ac84dc8b3f21ef19ad63031
work_keys_str_mv	AT senguptap modificationofporouspolyethylenescaffoldsforcellattachmentandproliferation AT surwasess modificationofporouspolyethylenescaffoldsforcellattachmentandproliferation AT prasadblv modificationofporouspolyethylenescaffoldsforcellattachmentandproliferation
_version_	1718401933068206080

Modification of porous polyethylene scaffolds for cell attachment and proliferation

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