Testosterone levels and type 2 diabetes in men: current knowledge and clinical implications

Anne M Beatrice, Deep Dutta, Manoj Kumar, Siddegowda Kumbenahalli Shivaprasad, Ankur Sinha, Sayantan Ray, Subhankar ChowdhuryDepartment of Endocrinology and Metabolism, Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Calcutta, India Abstract: Th...

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Autores principales: Beatrice AM, Dutta D, Kumar M, Shivaprasad KS, Sinha A, Ray S, Chowdhury S
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Publicado: Dove Medical Press 2014
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spelling oai:doaj.org-article:972f41bd8ab048f5a116782e9e62876f2021-12-02T02:03:35ZTestosterone levels and type 2 diabetes in men: current knowledge and clinical implications1178-7007https://doaj.org/article/972f41bd8ab048f5a116782e9e62876f2014-10-01T00:00:00Zhttp://www.dovepress.com/testosterone-levels-and-type-2-diabetes-in-men-current-knowledge-and-c-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007 Anne M Beatrice, Deep Dutta, Manoj Kumar, Siddegowda Kumbenahalli Shivaprasad, Ankur Sinha, Sayantan Ray, Subhankar ChowdhuryDepartment of Endocrinology and Metabolism, Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Calcutta, India Abstract: The relationship between testosterone and diabetes is an important issue, given the fact that diabetes is becoming a fast-growing epidemic, the morbidity associated with which is more disabling than the disease itself. Various studies have demonstrated the increasing prevalence of hypogonadism in diabetic subjects, but whether this is a cause or effect is still an area of active research. The past couple of decades have witnessed an increasing rate of testosterone prescriptions, even though the relationship between testosterone therapy and cardiovascular effects is still not conclusive. The studies done in this regard have shown conflicting results, and there is still a dearth of long-term, follow-up studies in this field. This paper reviews in brief the postulated mechanisms, observational studies, and interventional data regarding the adverse effects of testosterone therapy in type 2 diabetes mellitus, stressing the cardiovascular risks. Keywords: testosterone, hypogonadism, type 2 diabetes, cardiovascular events, quality of lifeBeatrice AMDutta DKumar MShivaprasad KSSinha ARay SChowdhury SDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2014, Iss default, Pp 481-486 (2014)
institution DOAJ
collection DOAJ
language EN
topic Specialties of internal medicine
RC581-951
spellingShingle Specialties of internal medicine
RC581-951
Beatrice AM
Dutta D
Kumar M
Shivaprasad KS
Sinha A
Ray S
Chowdhury S
Testosterone levels and type 2 diabetes in men: current knowledge and clinical implications
description Anne M Beatrice, Deep Dutta, Manoj Kumar, Siddegowda Kumbenahalli Shivaprasad, Ankur Sinha, Sayantan Ray, Subhankar ChowdhuryDepartment of Endocrinology and Metabolism, Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Calcutta, India Abstract: The relationship between testosterone and diabetes is an important issue, given the fact that diabetes is becoming a fast-growing epidemic, the morbidity associated with which is more disabling than the disease itself. Various studies have demonstrated the increasing prevalence of hypogonadism in diabetic subjects, but whether this is a cause or effect is still an area of active research. The past couple of decades have witnessed an increasing rate of testosterone prescriptions, even though the relationship between testosterone therapy and cardiovascular effects is still not conclusive. The studies done in this regard have shown conflicting results, and there is still a dearth of long-term, follow-up studies in this field. This paper reviews in brief the postulated mechanisms, observational studies, and interventional data regarding the adverse effects of testosterone therapy in type 2 diabetes mellitus, stressing the cardiovascular risks. Keywords: testosterone, hypogonadism, type 2 diabetes, cardiovascular events, quality of life
format article
author Beatrice AM
Dutta D
Kumar M
Shivaprasad KS
Sinha A
Ray S
Chowdhury S
author_facet Beatrice AM
Dutta D
Kumar M
Shivaprasad KS
Sinha A
Ray S
Chowdhury S
author_sort Beatrice AM
title Testosterone levels and type 2 diabetes in men: current knowledge and clinical implications
title_short Testosterone levels and type 2 diabetes in men: current knowledge and clinical implications
title_full Testosterone levels and type 2 diabetes in men: current knowledge and clinical implications
title_fullStr Testosterone levels and type 2 diabetes in men: current knowledge and clinical implications
title_full_unstemmed Testosterone levels and type 2 diabetes in men: current knowledge and clinical implications
title_sort testosterone levels and type 2 diabetes in men: current knowledge and clinical implications
publisher Dove Medical Press
publishDate 2014
url https://doaj.org/article/972f41bd8ab048f5a116782e9e62876f
work_keys_str_mv AT beatriceam testosteronelevelsandtype2diabetesinmencurrentknowledgeandclinicalimplications
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AT shivaprasadks testosteronelevelsandtype2diabetesinmencurrentknowledgeandclinicalimplications
AT sinhaa testosteronelevelsandtype2diabetesinmencurrentknowledgeandclinicalimplications
AT rays testosteronelevelsandtype2diabetesinmencurrentknowledgeandclinicalimplications
AT chowdhurys testosteronelevelsandtype2diabetesinmencurrentknowledgeandclinicalimplications
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