Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice

During the maternal-to-zygotic transition there is degradation of maternal proteins via the ubiquitin-proteasome system (UPS). Here, the authors show that in the embryo the maternally inherited epigenetic factor DPPA3/Stella/PGC7 is cleavage by the UPS and controls intracellular trafficking.

Guardado en:
Detalles Bibliográficos
Autores principales: Seung-Wook Shin, Edgar John Vogt, Maria Jimenez-Movilla, Boris Baibakov, Jurrien Dean
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/973311f9c5ad4366a689137556ac9020
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!