Prmary adenomyoepithelioma of the skin-a variant of apocrine mixed tumor?

Analogous to adenomyoepitheliomas of the breast, cutaneous adenomyoepithelioma is composed of two components, one being myoepithelial, the other ductal epithelial, and it lies in the spectrum of neoplasms having a “pure” myoepithelioma at one end and a mixed apocrine tumor at the other. We present...

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Autores principales: Elisabeth Reidl, Geoffrey J. Gottlieb
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Lenguaje:EN
Publicado: Mattioli1885 2012
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spelling oai:doaj.org-article:9734070f8c0045c281e3351a7677649e2021-11-17T08:33:15ZPrmary adenomyoepithelioma of the skin-a variant of apocrine mixed tumor?10.5826/dpc.0201a082160-9381https://doaj.org/article/9734070f8c0045c281e3351a7677649e2012-01-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/1151https://doaj.org/toc/2160-9381 Analogous to adenomyoepitheliomas of the breast, cutaneous adenomyoepithelioma is composed of two components, one being myoepithelial, the other ductal epithelial, and it lies in the spectrum of neoplasms having a “pure” myoepithelioma at one end and a mixed apocrine tumor at the other. We present the case of a 53-year-old woman with a 3 cm nodular lesion on her left forearm that had been present for many years. Histopathologic examination revealed a large lobulated neoplasm surrounded by a compressed fibrous pseudocapsule. Most of the cells that constituted the lesion displayed myoepithelial differentiation arranged in solid sheets, cords, and solitary units. Glandular and ductal structures with features of apocrine differentiation composed the second part of the neoplasm. The myoepithelial cellular component of the neoplasm stained for S100 protein and was negative for cytokeratin and carcinoembryonic antigen (CEA). Based on findings by conventional microscopy and immunohistochemistry, the neoplasm was classified as primary adenomyoepithelioma of the skin. Elisabeth ReidlGeoffrey J. GottliebMattioli1885articleadenomyoepitheliomaapocrine mixed tumormyoepitheliomaDermatologyRL1-803ENDermatology Practical & Conceptual (2012)
institution DOAJ
collection DOAJ
language EN
topic adenomyoepithelioma
apocrine mixed tumor
myoepithelioma
Dermatology
RL1-803
spellingShingle adenomyoepithelioma
apocrine mixed tumor
myoepithelioma
Dermatology
RL1-803
Elisabeth Reidl
Geoffrey J. Gottlieb
Prmary adenomyoepithelioma of the skin-a variant of apocrine mixed tumor?
description Analogous to adenomyoepitheliomas of the breast, cutaneous adenomyoepithelioma is composed of two components, one being myoepithelial, the other ductal epithelial, and it lies in the spectrum of neoplasms having a “pure” myoepithelioma at one end and a mixed apocrine tumor at the other. We present the case of a 53-year-old woman with a 3 cm nodular lesion on her left forearm that had been present for many years. Histopathologic examination revealed a large lobulated neoplasm surrounded by a compressed fibrous pseudocapsule. Most of the cells that constituted the lesion displayed myoepithelial differentiation arranged in solid sheets, cords, and solitary units. Glandular and ductal structures with features of apocrine differentiation composed the second part of the neoplasm. The myoepithelial cellular component of the neoplasm stained for S100 protein and was negative for cytokeratin and carcinoembryonic antigen (CEA). Based on findings by conventional microscopy and immunohistochemistry, the neoplasm was classified as primary adenomyoepithelioma of the skin.
format article
author Elisabeth Reidl
Geoffrey J. Gottlieb
author_facet Elisabeth Reidl
Geoffrey J. Gottlieb
author_sort Elisabeth Reidl
title Prmary adenomyoepithelioma of the skin-a variant of apocrine mixed tumor?
title_short Prmary adenomyoepithelioma of the skin-a variant of apocrine mixed tumor?
title_full Prmary adenomyoepithelioma of the skin-a variant of apocrine mixed tumor?
title_fullStr Prmary adenomyoepithelioma of the skin-a variant of apocrine mixed tumor?
title_full_unstemmed Prmary adenomyoepithelioma of the skin-a variant of apocrine mixed tumor?
title_sort prmary adenomyoepithelioma of the skin-a variant of apocrine mixed tumor?
publisher Mattioli1885
publishDate 2012
url https://doaj.org/article/9734070f8c0045c281e3351a7677649e
work_keys_str_mv AT elisabethreidl prmaryadenomyoepitheliomaoftheskinavariantofapocrinemixedtumor
AT geoffreyjgottlieb prmaryadenomyoepitheliomaoftheskinavariantofapocrinemixedtumor
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