Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates

The role of tissue mechanics in the regeneration of mucociliated epithelium in Xenopus is unclear. Here, the authors show that Xenopus ectoderm aggregates undergo epithelial-like phenotypic transition prior to differentiation of mucus-secreting goblet cells to enable regeneration.

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Autores principales:	Hye Young Kim, Timothy R. Jackson, Carsten Stuckenholz, Lance A. Davidson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/973608bc2abf45929471f292816a4fd9
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spelling	oai:doaj.org-article:973608bc2abf45929471f292816a4fd92021-12-02T17:31:08ZTissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates10.1038/s41467-020-14385-y2041-1723https://doaj.org/article/973608bc2abf45929471f292816a4fd92020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14385-yhttps://doaj.org/toc/2041-1723The role of tissue mechanics in the regeneration of mucociliated epithelium in Xenopus is unclear. Here, the authors show that Xenopus ectoderm aggregates undergo epithelial-like phenotypic transition prior to differentiation of mucus-secreting goblet cells to enable regeneration.Hye Young KimTimothy R. JacksonCarsten StuckenholzLance A. DavidsonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hye Young Kim Timothy R. Jackson Carsten Stuckenholz Lance A. Davidson Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates
description	The role of tissue mechanics in the regeneration of mucociliated epithelium in Xenopus is unclear. Here, the authors show that Xenopus ectoderm aggregates undergo epithelial-like phenotypic transition prior to differentiation of mucus-secreting goblet cells to enable regeneration.
format	article
author	Hye Young Kim Timothy R. Jackson Carsten Stuckenholz Lance A. Davidson
author_facet	Hye Young Kim Timothy R. Jackson Carsten Stuckenholz Lance A. Davidson
author_sort	Hye Young Kim
title	Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates
title_short	Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates
title_full	Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates
title_fullStr	Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates
title_full_unstemmed	Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates
title_sort	tissue mechanics drives regeneration of a mucociliated epidermis on the surface of xenopus embryonic aggregates
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/973608bc2abf45929471f292816a4fd9
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Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates

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