Comparison of Serum 25-Hydroxyvitamin D Levels in Children with and without Intussusception

BACKGROUND AND OBJECTIVE: Intussusception is the most common cause of intestinal obstruction and one of the most common causes of abdominal emergencies in children, which can lead to significant mortality and morbidity if left untreated. Since vitamin D acts as a hormone in the body and plays an imp...

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Autores principales:	MR Esmaeili Doki, S Mehrabani, SF Hashemi, M Hajiahmadi, M Pournasrollah, A Hadipour, S Osia, HG Nooreddini
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2020
Materias:	intussusception vitamin d intestinal obstruction child. Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/973ec85059174678b407026516f3e604
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spelling	oai:doaj.org-article:973ec85059174678b407026516f3e6042021-11-09T10:15:54ZComparison of Serum 25-Hydroxyvitamin D Levels in Children with and without Intussusception1561-41072251-7170https://doaj.org/article/973ec85059174678b407026516f3e6042020-03-01T00:00:00Zhttp://jbums.org/article-1-9658-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Intussusception is the most common cause of intestinal obstruction and one of the most common causes of abdominal emergencies in children, which can lead to significant mortality and morbidity if left untreated. Since vitamin D acts as a hormone in the body and plays an important role in preventing infectious and non-infectious diseases and regulating the intestinal immune response, this study was performed to investigate the relationship between vitamin D levels and the occurrence of intussusception. METHODS: This case-control study was performed on 86 children under 6 years old and above the neonatal age referred to Amirkola Children's Hospital in 2017-2018. The diagnosis of intussusception was made by ultrasound and the control group (without intussusception) was selected from patients with elective surgery other than intussusception. Vitamin D levels of children were assessed and compared in the two groups of children with and without intussusception. FINDINGS: In this study, 50 people were in the intussusception group and 36 people were in the control group. The mean age was 27.2±14.6 months in the intussusception group and 24.7±15.9 months in the control group (p=0.447). The mean serum 25-hydroxyvitamin D levels in children with intussusception was 36.5±14.4 ng/ml and in the control group was 32.7±13.1 ng/ml (p=0.212). CONCLUSION: According to the results of the present study, there was no association between serum 25-hydroxyvitamin D levels in children with and without intussusception and this vitamin was not associated with the occurrence of intussusception.MR Esmaeili DokiS MehrabaniSF HashemiM HajiahmadiM PournasrollahA HadipourS OsiaHG NooreddiniBabol University of Medical Sciencesarticleintussusceptionvitamin dintestinal obstructionchild.MedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 22, Iss 1, Pp 229-235 (2020)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	intussusception vitamin d intestinal obstruction child. Medicine R Medicine (General) R5-920
spellingShingle	intussusception vitamin d intestinal obstruction child. Medicine R Medicine (General) R5-920 MR Esmaeili Doki S Mehrabani SF Hashemi M Hajiahmadi M Pournasrollah A Hadipour S Osia HG Nooreddini Comparison of Serum 25-Hydroxyvitamin D Levels in Children with and without Intussusception
description	BACKGROUND AND OBJECTIVE: Intussusception is the most common cause of intestinal obstruction and one of the most common causes of abdominal emergencies in children, which can lead to significant mortality and morbidity if left untreated. Since vitamin D acts as a hormone in the body and plays an important role in preventing infectious and non-infectious diseases and regulating the intestinal immune response, this study was performed to investigate the relationship between vitamin D levels and the occurrence of intussusception. METHODS: This case-control study was performed on 86 children under 6 years old and above the neonatal age referred to Amirkola Children's Hospital in 2017-2018. The diagnosis of intussusception was made by ultrasound and the control group (without intussusception) was selected from patients with elective surgery other than intussusception. Vitamin D levels of children were assessed and compared in the two groups of children with and without intussusception. FINDINGS: In this study, 50 people were in the intussusception group and 36 people were in the control group. The mean age was 27.2±14.6 months in the intussusception group and 24.7±15.9 months in the control group (p=0.447). The mean serum 25-hydroxyvitamin D levels in children with intussusception was 36.5±14.4 ng/ml and in the control group was 32.7±13.1 ng/ml (p=0.212). CONCLUSION: According to the results of the present study, there was no association between serum 25-hydroxyvitamin D levels in children with and without intussusception and this vitamin was not associated with the occurrence of intussusception.
format	article
author	MR Esmaeili Doki S Mehrabani SF Hashemi M Hajiahmadi M Pournasrollah A Hadipour S Osia HG Nooreddini
author_facet	MR Esmaeili Doki S Mehrabani SF Hashemi M Hajiahmadi M Pournasrollah A Hadipour S Osia HG Nooreddini
author_sort	MR Esmaeili Doki
title	Comparison of Serum 25-Hydroxyvitamin D Levels in Children with and without Intussusception
title_short	Comparison of Serum 25-Hydroxyvitamin D Levels in Children with and without Intussusception
title_full	Comparison of Serum 25-Hydroxyvitamin D Levels in Children with and without Intussusception
title_fullStr	Comparison of Serum 25-Hydroxyvitamin D Levels in Children with and without Intussusception
title_full_unstemmed	Comparison of Serum 25-Hydroxyvitamin D Levels in Children with and without Intussusception
title_sort	comparison of serum 25-hydroxyvitamin d levels in children with and without intussusception
publisher	Babol University of Medical Sciences
publishDate	2020
url	https://doaj.org/article/973ec85059174678b407026516f3e604
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Comparison of Serum 25-Hydroxyvitamin D Levels in Children with and without Intussusception

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