Treatment of systemic-onset juvenile arthritis with canakinumab
Joachim Peitz, Gerd Horneff Pediatric Rheumatology Centre, Department of General Pediatrics and Neonatology, Asklepios Clinic, Sankt Augustin, Germany Abstract: Treatment of systemic-onset juvenile idiopathic arthritis is challenging, but the availability of cytokine antagonists targeting interleu...
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Dove Medical Press
2015
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oai:doaj.org-article:974a3e6cbe3c4fa79506ad41d2b574062021-12-02T02:46:03ZTreatment of systemic-onset juvenile arthritis with canakinumab1179-156Xhttps://doaj.org/article/974a3e6cbe3c4fa79506ad41d2b574062015-02-01T00:00:00Zhttp://www.dovepress.com/treatment-of-systemic-onset-juvenile-arthritis-with-canakinumab-peer-reviewed-article-OARRRhttps://doaj.org/toc/1179-156X Joachim Peitz, Gerd Horneff Pediatric Rheumatology Centre, Department of General Pediatrics and Neonatology, Asklepios Clinic, Sankt Augustin, Germany Abstract: Treatment of systemic-onset juvenile idiopathic arthritis is challenging, but the availability of cytokine antagonists targeting interleukin-1 and interleukin-6 have markedly advanced the therapeutic options. In this review, we focus on the current experience with canakinumab, an interleukin-1 monoclonal human antibody for the treatment of systemic-onset juvenile idiopathic arthritis and describe its efficacy and safety. Canakinumab is an important, safe, and valid drug in the treatment of systemic-onset juvenile idiopathic arthritis. Keywords: anakinra, canakinumab, interleukin-1, interleukin-6, systemic-onset juvenile idiopathic arthritisPeitz JHorneff GDove Medical PressarticleDiseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol 2015, Iss default, Pp 23-31 (2015) |
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DOAJ |
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DOAJ |
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EN |
topic |
Diseases of the musculoskeletal system RC925-935 |
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Diseases of the musculoskeletal system RC925-935 Peitz J Horneff G Treatment of systemic-onset juvenile arthritis with canakinumab |
description |
Joachim Peitz, Gerd Horneff Pediatric Rheumatology Centre, Department of General Pediatrics and Neonatology, Asklepios Clinic, Sankt Augustin, Germany Abstract: Treatment of systemic-onset juvenile idiopathic arthritis is challenging, but the availability of cytokine antagonists targeting interleukin-1 and interleukin-6 have markedly advanced the therapeutic options. In this review, we focus on the current experience with canakinumab, an interleukin-1 monoclonal human antibody for the treatment of systemic-onset juvenile idiopathic arthritis and describe its efficacy and safety. Canakinumab is an important, safe, and valid drug in the treatment of systemic-onset juvenile idiopathic arthritis. Keywords: anakinra, canakinumab, interleukin-1, interleukin-6, systemic-onset juvenile idiopathic arthritis |
format |
article |
author |
Peitz J Horneff G |
author_facet |
Peitz J Horneff G |
author_sort |
Peitz J |
title |
Treatment of systemic-onset juvenile arthritis with canakinumab |
title_short |
Treatment of systemic-onset juvenile arthritis with canakinumab |
title_full |
Treatment of systemic-onset juvenile arthritis with canakinumab |
title_fullStr |
Treatment of systemic-onset juvenile arthritis with canakinumab |
title_full_unstemmed |
Treatment of systemic-onset juvenile arthritis with canakinumab |
title_sort |
treatment of systemic-onset juvenile arthritis with canakinumab |
publisher |
Dove Medical Press |
publishDate |
2015 |
url |
https://doaj.org/article/974a3e6cbe3c4fa79506ad41d2b57406 |
work_keys_str_mv |
AT peitzj treatmentofsystemiconsetjuvenilearthritiswithcanakinumab AT horneffg treatmentofsystemiconsetjuvenilearthritiswithcanakinumab |
_version_ |
1718402179265462272 |