Genetic study links components of the autonomous nervous system to heart-rate profile during exercise
Response of the heart rate (HR) to exercise is associated with cardiac fitness and risk of cardiac death. Here, in a genome-wide association study, Verweij et al. identify 23 loci for HR increase during exercise or HR recovery, and highlight pleiotropy with blood pressure by polygenic risk score ana...
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Nature Portfolio
2018
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oai:doaj.org-article:975588f1fb784007ba2246fad40b96282021-12-02T17:32:29ZGenetic study links components of the autonomous nervous system to heart-rate profile during exercise10.1038/s41467-018-03395-62041-1723https://doaj.org/article/975588f1fb784007ba2246fad40b96282018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03395-6https://doaj.org/toc/2041-1723Response of the heart rate (HR) to exercise is associated with cardiac fitness and risk of cardiac death. Here, in a genome-wide association study, Verweij et al. identify 23 loci for HR increase during exercise or HR recovery, and highlight pleiotropy with blood pressure by polygenic risk score analysis.Niek VerweijYordi J. van de VegtePim van der HarstNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
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Science Q Niek Verweij Yordi J. van de Vegte Pim van der Harst Genetic study links components of the autonomous nervous system to heart-rate profile during exercise |
description |
Response of the heart rate (HR) to exercise is associated with cardiac fitness and risk of cardiac death. Here, in a genome-wide association study, Verweij et al. identify 23 loci for HR increase during exercise or HR recovery, and highlight pleiotropy with blood pressure by polygenic risk score analysis. |
format |
article |
author |
Niek Verweij Yordi J. van de Vegte Pim van der Harst |
author_facet |
Niek Verweij Yordi J. van de Vegte Pim van der Harst |
author_sort |
Niek Verweij |
title |
Genetic study links components of the autonomous nervous system to heart-rate profile during exercise |
title_short |
Genetic study links components of the autonomous nervous system to heart-rate profile during exercise |
title_full |
Genetic study links components of the autonomous nervous system to heart-rate profile during exercise |
title_fullStr |
Genetic study links components of the autonomous nervous system to heart-rate profile during exercise |
title_full_unstemmed |
Genetic study links components of the autonomous nervous system to heart-rate profile during exercise |
title_sort |
genetic study links components of the autonomous nervous system to heart-rate profile during exercise |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/975588f1fb784007ba2246fad40b9628 |
work_keys_str_mv |
AT niekverweij geneticstudylinkscomponentsoftheautonomousnervoussystemtoheartrateprofileduringexercise AT yordijvandevegte geneticstudylinkscomponentsoftheautonomousnervoussystemtoheartrateprofileduringexercise AT pimvanderharst geneticstudylinkscomponentsoftheautonomousnervoussystemtoheartrateprofileduringexercise |
_version_ |
1718380263167229952 |