Genetic study links components of the autonomous nervous system to heart-rate profile during exercise

Response of the heart rate (HR) to exercise is associated with cardiac fitness and risk of cardiac death. Here, in a genome-wide association study, Verweij et al. identify 23 loci for HR increase during exercise or HR recovery, and highlight pleiotropy with blood pressure by polygenic risk score ana...

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Autores principales: Niek Verweij, Yordi J. van de Vegte, Pim van der Harst
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/975588f1fb784007ba2246fad40b9628
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spelling oai:doaj.org-article:975588f1fb784007ba2246fad40b96282021-12-02T17:32:29ZGenetic study links components of the autonomous nervous system to heart-rate profile during exercise10.1038/s41467-018-03395-62041-1723https://doaj.org/article/975588f1fb784007ba2246fad40b96282018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03395-6https://doaj.org/toc/2041-1723Response of the heart rate (HR) to exercise is associated with cardiac fitness and risk of cardiac death. Here, in a genome-wide association study, Verweij et al. identify 23 loci for HR increase during exercise or HR recovery, and highlight pleiotropy with blood pressure by polygenic risk score analysis.Niek VerweijYordi J. van de VegtePim van der HarstNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Niek Verweij
Yordi J. van de Vegte
Pim van der Harst
Genetic study links components of the autonomous nervous system to heart-rate profile during exercise
description Response of the heart rate (HR) to exercise is associated with cardiac fitness and risk of cardiac death. Here, in a genome-wide association study, Verweij et al. identify 23 loci for HR increase during exercise or HR recovery, and highlight pleiotropy with blood pressure by polygenic risk score analysis.
format article
author Niek Verweij
Yordi J. van de Vegte
Pim van der Harst
author_facet Niek Verweij
Yordi J. van de Vegte
Pim van der Harst
author_sort Niek Verweij
title Genetic study links components of the autonomous nervous system to heart-rate profile during exercise
title_short Genetic study links components of the autonomous nervous system to heart-rate profile during exercise
title_full Genetic study links components of the autonomous nervous system to heart-rate profile during exercise
title_fullStr Genetic study links components of the autonomous nervous system to heart-rate profile during exercise
title_full_unstemmed Genetic study links components of the autonomous nervous system to heart-rate profile during exercise
title_sort genetic study links components of the autonomous nervous system to heart-rate profile during exercise
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/975588f1fb784007ba2246fad40b9628
work_keys_str_mv AT niekverweij geneticstudylinkscomponentsoftheautonomousnervoussystemtoheartrateprofileduringexercise
AT yordijvandevegte geneticstudylinkscomponentsoftheautonomousnervoussystemtoheartrateprofileduringexercise
AT pimvanderharst geneticstudylinkscomponentsoftheautonomousnervoussystemtoheartrateprofileduringexercise
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