Using individual networks to identify treatment targets for eating disorder treatment: a proof-of-concept study and initial data

Plain English Summary Eating disorders are severe psychiatric illnesses that carry high mortality, morbidity, and societal and personal burden. Treatments for eating disorders only work in 50% of patients, signifying a great need to improve treatments. One reason that treatments may not work, is bec...

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Autores principales: Cheri A. Levinson, Rowan A. Hunt, Ani C. Keshishian, Mackenzie L. Brown, Irina Vanzhula, Caroline Christian, Leigh C. Brosof, Brenna M. Williams
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/97584db422914cbe82d7c5daa8b5fe54
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Sumario:Plain English Summary Eating disorders are severe psychiatric illnesses that carry high mortality, morbidity, and societal and personal burden. Treatments for eating disorders only work in 50% of patients, signifying a great need to improve treatments. One reason that treatments may not work, is because eating disorders vary substantially from one individual to the next, which existing treatments do not fully consider. The current study (N = 34 participants with an eating disorder diagnosis) uses a new modeling technique to identify which symptoms should be targeted in treatment in a personalized manner. As expected, we found that, using this modeling technique, symptoms that should be targeted in treatment vary considerably. We discuss how to use this modeling technique to identify individual treatment targets and ways in which the field can use this strategy to improve existing and create new treatments.