A single donor is sufficient to produce a highly functional in vitro antibody library
Here, the authors construct and validate an in vitro antibody library from a single, healthy donor. They demonstrate the functionality of the library using several therapeutically relevant targets and were able to obtain many different antibodies with the desired biophysical properties.
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Autores principales: | M. Frank Erasmus, Sara D’Angelo, Fortunato Ferrara, Leslie Naranjo, André A. Teixeira, Rebecca Buonpane, Shaun M. Stewart, Horacio G. Nastri, Andrew R. M. Bradbury |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/97589959248d40069c6d04e7cbd5a7d0 |
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