Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment

Aim. The aim of this study is to assess the therapeutic efficacy of alpha-lipoic acid in patients with type 2 diabetes mellitus (DM) and non-proliferativediabetic retinopathy. Materials and methods. 47 patients with mild to moderate non-proliferative diabetic retinopathy were included in this tria...

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Autores principales:	Tatiana Yul'evna Demidova, Yulia Alexandrovna Trakhtenberg
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2011
Materias:	diabetes mellitus complications retinopathy Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/975df920f71a4061900734e8e10e8d96
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spelling	oai:doaj.org-article:975df920f71a4061900734e8e10e8d962021-11-14T09:00:16ZAlpha-lipoic acid in non-proliferative diabetic retinopathy treatment2072-03512072-037810.14341/2072-0351-5823https://doaj.org/article/975df920f71a4061900734e8e10e8d962011-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5823https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. The aim of this study is to assess the therapeutic efficacy of alpha-lipoic acid in patients with type 2 diabetes mellitus (DM) and non-proliferativediabetic retinopathy. Materials and methods. 47 patients with mild to moderate non-proliferative diabetic retinopathy were included in this trial. Dynamics of ophthalmologicparameters were assessed by means of stereoscopic photography of ocular fundus. Patients were examined every 6 months in order to registernew cases of clinically significant macular oedema. Results. During 24 months follow-up period, patients treated with 600 mg of alpha-lipoic acid showed stabilization in development of diabetic retinopathy.New cases of macular oedema, as well as transition into a more severe stage of retonopathy were less common in those patients. Vision andcontrast sensation also remained stable in the majority of participants from experimental group.Conclusions. 600 mg of alpha-lipoic acid may be recommended for patients with type 2 DM as part of complex therapyTatiana Yul'evna DemidovaYulia Alexandrovna TrakhtenbergEndocrinology Research Centrearticlediabetes mellituscomplicationsretinopathyNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 14, Iss 4, Pp 82-86 (2011)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	diabetes mellitus complications retinopathy Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	diabetes mellitus complications retinopathy Nutritional diseases. Deficiency diseases RC620-627 Tatiana Yul'evna Demidova Yulia Alexandrovna Trakhtenberg Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment
description	Aim. The aim of this study is to assess the therapeutic efficacy of alpha-lipoic acid in patients with type 2 diabetes mellitus (DM) and non-proliferativediabetic retinopathy. Materials and methods. 47 patients with mild to moderate non-proliferative diabetic retinopathy were included in this trial. Dynamics of ophthalmologicparameters were assessed by means of stereoscopic photography of ocular fundus. Patients were examined every 6 months in order to registernew cases of clinically significant macular oedema. Results. During 24 months follow-up period, patients treated with 600 mg of alpha-lipoic acid showed stabilization in development of diabetic retinopathy.New cases of macular oedema, as well as transition into a more severe stage of retonopathy were less common in those patients. Vision andcontrast sensation also remained stable in the majority of participants from experimental group.Conclusions. 600 mg of alpha-lipoic acid may be recommended for patients with type 2 DM as part of complex therapy
format	article
author	Tatiana Yul'evna Demidova Yulia Alexandrovna Trakhtenberg
author_facet	Tatiana Yul'evna Demidova Yulia Alexandrovna Trakhtenberg
author_sort	Tatiana Yul'evna Demidova
title	Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment
title_short	Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment
title_full	Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment
title_fullStr	Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment
title_full_unstemmed	Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment
title_sort	alpha-lipoic acid in non-proliferative diabetic retinopathy treatment
publisher	Endocrinology Research Centre
publishDate	2011
url	https://doaj.org/article/975df920f71a4061900734e8e10e8d96
work_keys_str_mv	AT tatianayulevnademidova alphalipoicacidinnonproliferativediabeticretinopathytreatment AT yuliaalexandrovnatrakhtenberg alphalipoicacidinnonproliferativediabeticretinopathytreatment
_version_	1718429596145156096

Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment

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