Cellular connectomes as arbiters of local circuit models in the cerebral cortex

Large-scale connectomes from the mammalian brain are becoming available, but it remains unclear how informative these are for the distinction of circuit models. Here, the authors use connectome statistics to test competing models of local cortical circuits with approximate Bayesian computation.

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Autores principales:	Emmanuel Klinger, Alessandro Motta, Carsten Marr, Fabian J. Theis, Moritz Helmstaedter
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/976449bebfec47c3a21f9ec50a671ef2
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spelling	oai:doaj.org-article:976449bebfec47c3a21f9ec50a671ef22021-12-02T16:50:26ZCellular connectomes as arbiters of local circuit models in the cerebral cortex10.1038/s41467-021-22856-z2041-1723https://doaj.org/article/976449bebfec47c3a21f9ec50a671ef22021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22856-zhttps://doaj.org/toc/2041-1723Large-scale connectomes from the mammalian brain are becoming available, but it remains unclear how informative these are for the distinction of circuit models. Here, the authors use connectome statistics to test competing models of local cortical circuits with approximate Bayesian computation.Emmanuel KlingerAlessandro MottaCarsten MarrFabian J. TheisMoritz HelmstaedterNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Emmanuel Klinger Alessandro Motta Carsten Marr Fabian J. Theis Moritz Helmstaedter Cellular connectomes as arbiters of local circuit models in the cerebral cortex
description	Large-scale connectomes from the mammalian brain are becoming available, but it remains unclear how informative these are for the distinction of circuit models. Here, the authors use connectome statistics to test competing models of local cortical circuits with approximate Bayesian computation.
format	article
author	Emmanuel Klinger Alessandro Motta Carsten Marr Fabian J. Theis Moritz Helmstaedter
author_facet	Emmanuel Klinger Alessandro Motta Carsten Marr Fabian J. Theis Moritz Helmstaedter
author_sort	Emmanuel Klinger
title	Cellular connectomes as arbiters of local circuit models in the cerebral cortex
title_short	Cellular connectomes as arbiters of local circuit models in the cerebral cortex
title_full	Cellular connectomes as arbiters of local circuit models in the cerebral cortex
title_fullStr	Cellular connectomes as arbiters of local circuit models in the cerebral cortex
title_full_unstemmed	Cellular connectomes as arbiters of local circuit models in the cerebral cortex
title_sort	cellular connectomes as arbiters of local circuit models in the cerebral cortex
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/976449bebfec47c3a21f9ec50a671ef2
work_keys_str_mv	AT emmanuelklinger cellularconnectomesasarbitersoflocalcircuitmodelsinthecerebralcortex AT alessandromotta cellularconnectomesasarbitersoflocalcircuitmodelsinthecerebralcortex AT carstenmarr cellularconnectomesasarbitersoflocalcircuitmodelsinthecerebralcortex AT fabianjtheis cellularconnectomesasarbitersoflocalcircuitmodelsinthecerebralcortex AT moritzhelmstaedter cellularconnectomesasarbitersoflocalcircuitmodelsinthecerebralcortex
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Cellular connectomes as arbiters of local circuit models in the cerebral cortex

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