Spatial rearrangement of the Streptomyces venezuelae linear chromosome during sporogenic development

Streptomyces bacteria have a linear chromosome and a complex life cycle, including development of multi-genomic hyphae that differentiate into mono-genomic exospores. Here, Szafran et al. show that the chromosome of Streptomyces venezuelae undergoes substantial remodelling during sporulation, from a...

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Autores principales: Marcin J. Szafran, Tomasz Małecki, Agnieszka Strzałka, Katarzyna Pawlikiewicz, Julia Duława, Anna Zarek, Agnieszka Kois-Ostrowska, Kim C. Findlay, Tung B. K. Le, Dagmara Jakimowicz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9766f0380f5e4e4a8dcdc34cfb142868
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Sumario:Streptomyces bacteria have a linear chromosome and a complex life cycle, including development of multi-genomic hyphae that differentiate into mono-genomic exospores. Here, Szafran et al. show that the chromosome of Streptomyces venezuelae undergoes substantial remodelling during sporulation, from an ‘open’ to a ‘closed’ conformation.