Assessment of IVIG treatment in children and its complications, Babol, 1999-2004

BACKGROUND AND OBJECTIVE: IVIG is used in patients incapable of producing antibodies and in autoimmune disorders. IVIG infusion rarely causes undesirable reactions due to the speed of infusion. So, this study was performed to determine the indications and complications of IVIG infusion.METHODS: This...

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Autores principales:	E Mohammad Zadeh I, A, Atar Zadeh, A Arzani, A Tamaddoni
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2006
Materias:	immunoglobulin kawasaki immune thrombocytopenic purpura Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/976ec39a5ad047e892efe09fa8b96e15
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spelling	oai:doaj.org-article:976ec39a5ad047e892efe09fa8b96e152021-11-10T09:12:42ZAssessment of IVIG treatment in children and its complications, Babol, 1999-20041561-41072251-7170https://doaj.org/article/976ec39a5ad047e892efe09fa8b96e152006-04-01T00:00:00Zhttp://jbums.org/article-1-2553-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: IVIG is used in patients incapable of producing antibodies and in autoimmune disorders. IVIG infusion rarely causes undesirable reactions due to the speed of infusion. So, this study was performed to determine the indications and complications of IVIG infusion.METHODS: This descriptive study was performed on 265 patients, hospitalized in Amirkola pediatric hospital, needing IVIG infusions, from October 1999 to June 2004. Data was analyzed by SPSS. T-test, chi square and fisher exact test were used to compare drug complications based on age and speed of infusion in two genders.FINDINGS: In this research, 265 patients with 871 infusions were studied. One hundred and thirty one patients (49.4%) were male and 134 (50.6%) were female. Two patients (0.7%) had autoimmune hemolytic anemia, one patient (0.3%) had ataxia telangectasia, 9 patients (3.4%) had refractory seizure, 2 patients (0.7%) had guillain-barre syndrome, 83 patients (31.3%) had immune thrombocytopenic purpura, 46 patients (17.3%) had kawasaki, 51 patients (19.2%) had immunodeficiency and 72 patients (27.1%) were premature neonates. Among the studied patients, 17 infusions (1.95%) had complications, which were mild in 14 patients (82.5%), moderate in 2 patients (11.7%) and severe in 1 patient (5.8%). Complication was the same in both genders, and it had a significant difference with the speed of drug infusion (p<0.05).CONCLUSION: The most common cause of IVIG infusion is immune thrombocytopenic purpura. Complications are usually mild and had relationship with the speed of drug infusion.E Mohammad Zadeh I, A, Atar ZadehA ArzaniA TamaddoniBabol University of Medical Sciencesarticleimmunoglobulinkawasakiimmune thrombocytopenic purpuraMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 8, Iss 2, Pp 32-35 (2006)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	immunoglobulin kawasaki immune thrombocytopenic purpura Medicine R Medicine (General) R5-920
spellingShingle	immunoglobulin kawasaki immune thrombocytopenic purpura Medicine R Medicine (General) R5-920 E Mohammad Zadeh I, A, Atar Zadeh A Arzani A Tamaddoni Assessment of IVIG treatment in children and its complications, Babol, 1999-2004
description	BACKGROUND AND OBJECTIVE: IVIG is used in patients incapable of producing antibodies and in autoimmune disorders. IVIG infusion rarely causes undesirable reactions due to the speed of infusion. So, this study was performed to determine the indications and complications of IVIG infusion.METHODS: This descriptive study was performed on 265 patients, hospitalized in Amirkola pediatric hospital, needing IVIG infusions, from October 1999 to June 2004. Data was analyzed by SPSS. T-test, chi square and fisher exact test were used to compare drug complications based on age and speed of infusion in two genders.FINDINGS: In this research, 265 patients with 871 infusions were studied. One hundred and thirty one patients (49.4%) were male and 134 (50.6%) were female. Two patients (0.7%) had autoimmune hemolytic anemia, one patient (0.3%) had ataxia telangectasia, 9 patients (3.4%) had refractory seizure, 2 patients (0.7%) had guillain-barre syndrome, 83 patients (31.3%) had immune thrombocytopenic purpura, 46 patients (17.3%) had kawasaki, 51 patients (19.2%) had immunodeficiency and 72 patients (27.1%) were premature neonates. Among the studied patients, 17 infusions (1.95%) had complications, which were mild in 14 patients (82.5%), moderate in 2 patients (11.7%) and severe in 1 patient (5.8%). Complication was the same in both genders, and it had a significant difference with the speed of drug infusion (p<0.05).CONCLUSION: The most common cause of IVIG infusion is immune thrombocytopenic purpura. Complications are usually mild and had relationship with the speed of drug infusion.
format	article
author	E Mohammad Zadeh I, A, Atar Zadeh A Arzani A Tamaddoni
author_facet	E Mohammad Zadeh I, A, Atar Zadeh A Arzani A Tamaddoni
author_sort	E Mohammad Zadeh I, A, Atar Zadeh
title	Assessment of IVIG treatment in children and its complications, Babol, 1999-2004
title_short	Assessment of IVIG treatment in children and its complications, Babol, 1999-2004
title_full	Assessment of IVIG treatment in children and its complications, Babol, 1999-2004
title_fullStr	Assessment of IVIG treatment in children and its complications, Babol, 1999-2004
title_full_unstemmed	Assessment of IVIG treatment in children and its complications, Babol, 1999-2004
title_sort	assessment of ivig treatment in children and its complications, babol, 1999-2004
publisher	Babol University of Medical Sciences
publishDate	2006
url	https://doaj.org/article/976ec39a5ad047e892efe09fa8b96e15
work_keys_str_mv	AT emohammadzadehiaatarzadeh assessmentofivigtreatmentinchildrenanditscomplicationsbabol19992004 AT aarzani assessmentofivigtreatmentinchildrenanditscomplicationsbabol19992004 AT atamaddoni assessmentofivigtreatmentinchildrenanditscomplicationsbabol19992004
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Assessment of IVIG treatment in children and its complications, Babol, 1999-2004

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