JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling

Morphogens regulate growth and pattern in vertebrate and invertebrate limbs. Here, the authors show that the JAK/STAT pathway promotes the growth of the Hedgehog-producing cell population in theDrosophilawing, thereby allowing the stable localization of the BMP/Dpp organizer.

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Autores principales:	Carles Recasens-Alvarez, Ana Ferreira, Marco Milán
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/977a2cedc31b45d0909673b32b8e5572
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spelling	oai:doaj.org-article:977a2cedc31b45d0909673b32b8e55722021-12-02T14:42:10ZJAK/STAT controls organ size and fate specification by regulating morphogen production and signalling10.1038/ncomms138152041-1723https://doaj.org/article/977a2cedc31b45d0909673b32b8e55722017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms13815https://doaj.org/toc/2041-1723Morphogens regulate growth and pattern in vertebrate and invertebrate limbs. Here, the authors show that the JAK/STAT pathway promotes the growth of the Hedgehog-producing cell population in theDrosophilawing, thereby allowing the stable localization of the BMP/Dpp organizer.Carles Recasens-AlvarezAna FerreiraMarco MilánNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Carles Recasens-Alvarez Ana Ferreira Marco Milán JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling
description	Morphogens regulate growth and pattern in vertebrate and invertebrate limbs. Here, the authors show that the JAK/STAT pathway promotes the growth of the Hedgehog-producing cell population in theDrosophilawing, thereby allowing the stable localization of the BMP/Dpp organizer.
format	article
author	Carles Recasens-Alvarez Ana Ferreira Marco Milán
author_facet	Carles Recasens-Alvarez Ana Ferreira Marco Milán
author_sort	Carles Recasens-Alvarez
title	JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling
title_short	JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling
title_full	JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling
title_fullStr	JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling
title_full_unstemmed	JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling
title_sort	jak/stat controls organ size and fate specification by regulating morphogen production and signalling
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/977a2cedc31b45d0909673b32b8e5572
work_keys_str_mv	AT carlesrecasensalvarez jakstatcontrolsorgansizeandfatespecificationbyregulatingmorphogenproductionandsignalling AT anaferreira jakstatcontrolsorgansizeandfatespecificationbyregulatingmorphogenproductionandsignalling AT marcomilan jakstatcontrolsorgansizeandfatespecificationbyregulatingmorphogenproductionandsignalling
_version_	1718389766248988672

JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling

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