An Evolutionarily Conserved Mechanism for Intrinsic and Transferable Polymyxin Resistance
ABSTRACT Polymyxins, a family of cationic antimicrobial cyclic peptides, act as a last line of defense against severe infections by Gram-negative pathogens with carbapenem resistance. In addition to the intrinsic resistance to polymyxin E (colistin) conferred by Neisseria eptA, the plasmid-borne mob...
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Autores principales: | Yongchang Xu, Wenhui Wei, Sheng Lei, Jingxia Lin, Swaminath Srinivas, Youjun Feng |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2018
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Acceso en línea: | https://doaj.org/article/977dbc397dc24d05840738adaebbe8c4 |
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