Analysis of Clinical Manifestations of Acute and Chronic Brucellosis in Patients Admitted to a Public General Hospital in Northern China

Chang-Min Liu,1,&ast; Bing Suo,2,&ast; Yan Zhang3,&ast; 1General Hospital of Heilongjiang Province Land Reclamation Bureau Infectious Disease Department, Harbin, 150088, People’s Republic of China; 2General Hospital of Heilongjiang Province Land Reclamation Bureau Scientific Research Sec...

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Autores principales:	Liu CM, Suo B, Zhang Y
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	brucellosis clinical characteristics acute phase chronic phase Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/97801400ca464850a1a3675923de7486
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spelling	oai:doaj.org-article:97801400ca464850a1a3675923de74862021-11-16T18:47:50ZAnalysis of Clinical Manifestations of Acute and Chronic Brucellosis in Patients Admitted to a Public General Hospital in Northern China1178-7074https://doaj.org/article/97801400ca464850a1a3675923de74862021-11-01T00:00:00Zhttps://www.dovepress.com/analysis-of-clinical-manifestations-of-acute-and-chronic-brucellosis-i-peer-reviewed-fulltext-article-IJGMhttps://doaj.org/toc/1178-7074Chang-Min Liu,1,&ast; Bing Suo,2,&ast; Yan Zhang3,&ast; 1General Hospital of Heilongjiang Province Land Reclamation Bureau Infectious Disease Department, Harbin, 150088, People’s Republic of China; 2General Hospital of Heilongjiang Province Land Reclamation Bureau Scientific Research Section, Harbin, 150088, People’s Republic of China; 3General Hospital of Heilongjiang Province Land Reclamation Bureau Clinical Laboratory, Harbin, 150088, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yan ZhangGeneral Hospital of Heilongjiang Province Land Reclamation Bureau Clinical Laboratory, No. 235, Hasuang Road, Nangang District, Harbin, Heilongjiang Province, 150088, People’s Republic of ChinaTel +86 451-55197654Fax +86 451-55197854Email zhangyanhhn@163.comObjective: To analyze the clinical features of patients with acute and chronic brucellosis in order to further improve the understanding of the disease.Methods: The clinical data of 144 patients with brucellosis who were admitted to our hospital were selected for retrospective analysis and were divided into two groups: the acute phase group (n = 86) and the chronic phase group (n = 58), and the clinical characteristics of the acute and chronic phases of the disease were analyzed. The χ2 test was used for countable data comparisons between the two groups.Results: Brucella melitensis was found as the contact organism in 61 patients (70.93%) in the acute phase group and in 12 patients (20.69%) in the chronic phase group (p < 0.01). Brucella abortus was found as the contact organism in 14 patients (16.28%) in the acute phase group and in 38 patients (65.52%) in the chronic phase group (p < 0.01). The results showed that the respective prevalence of fever, excessive sweating, splenomegaly, and lymph node enlargement were higher in the acute phase group than in the chronic phase group (p < 0.01). The respective prevalence of testicular swelling and pain were higher in the acute phase group than in the chronic phase group (p < 0.05), while the prevalence of joint and muscle pain was higher in the chronic phase group than in the acute phase group (p < 0.01).Conclusion: In Harbin, two types of clinical brucellosis, acute and chronic phase, infected sheep and cattle, respectively, are endemic at the same time, which complicates diagnosis. Besides, the clinical manifestations of brucellosis are complex and diverse, and they are often misdiagnosed and mistreated, leading to serious health injuries. Therefore, it is important to improve the understanding of disease characteristics in patients with acute and chronic brucellosis.Keywords: brucellosis, clinical characteristics, acute phase, chronic phaseLiu CMSuo BZhang YDove Medical Pressarticlebrucellosisclinical characteristicsacute phasechronic phaseMedicine (General)R5-920ENInternational Journal of General Medicine, Vol Volume 14, Pp 8311-8316 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	brucellosis clinical characteristics acute phase chronic phase Medicine (General) R5-920
spellingShingle	brucellosis clinical characteristics acute phase chronic phase Medicine (General) R5-920 Liu CM Suo B Zhang Y Analysis of Clinical Manifestations of Acute and Chronic Brucellosis in Patients Admitted to a Public General Hospital in Northern China
description	Chang-Min Liu,1,&ast; Bing Suo,2,&ast; Yan Zhang3,&ast; 1General Hospital of Heilongjiang Province Land Reclamation Bureau Infectious Disease Department, Harbin, 150088, People’s Republic of China; 2General Hospital of Heilongjiang Province Land Reclamation Bureau Scientific Research Section, Harbin, 150088, People’s Republic of China; 3General Hospital of Heilongjiang Province Land Reclamation Bureau Clinical Laboratory, Harbin, 150088, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yan ZhangGeneral Hospital of Heilongjiang Province Land Reclamation Bureau Clinical Laboratory, No. 235, Hasuang Road, Nangang District, Harbin, Heilongjiang Province, 150088, People’s Republic of ChinaTel +86 451-55197654Fax +86 451-55197854Email zhangyanhhn@163.comObjective: To analyze the clinical features of patients with acute and chronic brucellosis in order to further improve the understanding of the disease.Methods: The clinical data of 144 patients with brucellosis who were admitted to our hospital were selected for retrospective analysis and were divided into two groups: the acute phase group (n = 86) and the chronic phase group (n = 58), and the clinical characteristics of the acute and chronic phases of the disease were analyzed. The χ2 test was used for countable data comparisons between the two groups.Results: Brucella melitensis was found as the contact organism in 61 patients (70.93%) in the acute phase group and in 12 patients (20.69%) in the chronic phase group (p < 0.01). Brucella abortus was found as the contact organism in 14 patients (16.28%) in the acute phase group and in 38 patients (65.52%) in the chronic phase group (p < 0.01). The results showed that the respective prevalence of fever, excessive sweating, splenomegaly, and lymph node enlargement were higher in the acute phase group than in the chronic phase group (p < 0.01). The respective prevalence of testicular swelling and pain were higher in the acute phase group than in the chronic phase group (p < 0.05), while the prevalence of joint and muscle pain was higher in the chronic phase group than in the acute phase group (p < 0.01).Conclusion: In Harbin, two types of clinical brucellosis, acute and chronic phase, infected sheep and cattle, respectively, are endemic at the same time, which complicates diagnosis. Besides, the clinical manifestations of brucellosis are complex and diverse, and they are often misdiagnosed and mistreated, leading to serious health injuries. Therefore, it is important to improve the understanding of disease characteristics in patients with acute and chronic brucellosis.Keywords: brucellosis, clinical characteristics, acute phase, chronic phase
format	article
author	Liu CM Suo B Zhang Y
author_facet	Liu CM Suo B Zhang Y
author_sort	Liu CM
title	Analysis of Clinical Manifestations of Acute and Chronic Brucellosis in Patients Admitted to a Public General Hospital in Northern China
title_short	Analysis of Clinical Manifestations of Acute and Chronic Brucellosis in Patients Admitted to a Public General Hospital in Northern China
title_full	Analysis of Clinical Manifestations of Acute and Chronic Brucellosis in Patients Admitted to a Public General Hospital in Northern China
title_fullStr	Analysis of Clinical Manifestations of Acute and Chronic Brucellosis in Patients Admitted to a Public General Hospital in Northern China
title_full_unstemmed	Analysis of Clinical Manifestations of Acute and Chronic Brucellosis in Patients Admitted to a Public General Hospital in Northern China
title_sort	analysis of clinical manifestations of acute and chronic brucellosis in patients admitted to a public general hospital in northern china
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/97801400ca464850a1a3675923de7486
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Analysis of Clinical Manifestations of Acute and Chronic Brucellosis in Patients Admitted to a Public General Hospital in Northern China

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