High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya

Here, Nelson et al. use amplicon next-generation sequencing of two P. falciparum polymorphic gene regions to investigate the genetic similarity of parasite populations across time and space in a pediatric cohort in Kenya. They identify both micro- and macro-scale structuring of malaria parasites in...

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Autores principales: Cody S. Nelson, Kelsey M. Sumner, Elizabeth Freedman, Joseph W. Saelens, Andrew A. Obala, Judith N. Mangeni, Steve M. Taylor, Wendy P. O’Meara
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9781d83f0937441888046a9a8e212911
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spelling oai:doaj.org-article:9781d83f0937441888046a9a8e2129112021-12-02T15:35:31ZHigh-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya10.1038/s41467-019-13578-42041-1723https://doaj.org/article/9781d83f0937441888046a9a8e2129112019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13578-4https://doaj.org/toc/2041-1723Here, Nelson et al. use amplicon next-generation sequencing of two P. falciparum polymorphic gene regions to investigate the genetic similarity of parasite populations across time and space in a pediatric cohort in Kenya. They identify both micro- and macro-scale structuring of malaria parasites in this high-transmission setting, which could inform future intervention strategies.Cody S. NelsonKelsey M. SumnerElizabeth FreedmanJoseph W. SaelensAndrew A. ObalaJudith N. MangeniSteve M. TaylorWendy P. O’MearaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Cody S. Nelson
Kelsey M. Sumner
Elizabeth Freedman
Joseph W. Saelens
Andrew A. Obala
Judith N. Mangeni
Steve M. Taylor
Wendy P. O’Meara
High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
description Here, Nelson et al. use amplicon next-generation sequencing of two P. falciparum polymorphic gene regions to investigate the genetic similarity of parasite populations across time and space in a pediatric cohort in Kenya. They identify both micro- and macro-scale structuring of malaria parasites in this high-transmission setting, which could inform future intervention strategies.
format article
author Cody S. Nelson
Kelsey M. Sumner
Elizabeth Freedman
Joseph W. Saelens
Andrew A. Obala
Judith N. Mangeni
Steve M. Taylor
Wendy P. O’Meara
author_facet Cody S. Nelson
Kelsey M. Sumner
Elizabeth Freedman
Joseph W. Saelens
Andrew A. Obala
Judith N. Mangeni
Steve M. Taylor
Wendy P. O’Meara
author_sort Cody S. Nelson
title High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
title_short High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
title_full High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
title_fullStr High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
title_full_unstemmed High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
title_sort high-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in kenya
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/9781d83f0937441888046a9a8e212911
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