High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
Here, Nelson et al. use amplicon next-generation sequencing of two P. falciparum polymorphic gene regions to investigate the genetic similarity of parasite populations across time and space in a pediatric cohort in Kenya. They identify both micro- and macro-scale structuring of malaria parasites in...
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Nature Portfolio
2019
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oai:doaj.org-article:9781d83f0937441888046a9a8e2129112021-12-02T15:35:31ZHigh-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya10.1038/s41467-019-13578-42041-1723https://doaj.org/article/9781d83f0937441888046a9a8e2129112019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13578-4https://doaj.org/toc/2041-1723Here, Nelson et al. use amplicon next-generation sequencing of two P. falciparum polymorphic gene regions to investigate the genetic similarity of parasite populations across time and space in a pediatric cohort in Kenya. They identify both micro- and macro-scale structuring of malaria parasites in this high-transmission setting, which could inform future intervention strategies.Cody S. NelsonKelsey M. SumnerElizabeth FreedmanJoseph W. SaelensAndrew A. ObalaJudith N. MangeniSteve M. TaylorWendy P. O’MearaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q |
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Science Q Cody S. Nelson Kelsey M. Sumner Elizabeth Freedman Joseph W. Saelens Andrew A. Obala Judith N. Mangeni Steve M. Taylor Wendy P. O’Meara High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya |
description |
Here, Nelson et al. use amplicon next-generation sequencing of two P. falciparum polymorphic gene regions to investigate the genetic similarity of parasite populations across time and space in a pediatric cohort in Kenya. They identify both micro- and macro-scale structuring of malaria parasites in this high-transmission setting, which could inform future intervention strategies. |
format |
article |
author |
Cody S. Nelson Kelsey M. Sumner Elizabeth Freedman Joseph W. Saelens Andrew A. Obala Judith N. Mangeni Steve M. Taylor Wendy P. O’Meara |
author_facet |
Cody S. Nelson Kelsey M. Sumner Elizabeth Freedman Joseph W. Saelens Andrew A. Obala Judith N. Mangeni Steve M. Taylor Wendy P. O’Meara |
author_sort |
Cody S. Nelson |
title |
High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya |
title_short |
High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya |
title_full |
High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya |
title_fullStr |
High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya |
title_full_unstemmed |
High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya |
title_sort |
high-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in kenya |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/9781d83f0937441888046a9a8e212911 |
work_keys_str_mv |
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1718386549039562752 |