Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease is characterized by the formation of cysts in the kidney. Here the authors show that cystic extracellular vesicles/exosomes play a critical role in regulating the biology and function of adjacent cells, including renal epithelial cells, fibroblasts and ma...

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Autores principales:	Hao Ding, Linda Xiaoyan Li, Peter C. Harris, Junwei Yang, Xiaogang Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/978a2efe63ee4aecbb0e7b5a78ffde38
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spelling	oai:doaj.org-article:978a2efe63ee4aecbb0e7b5a78ffde382021-12-02T16:23:44ZExtracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease10.1038/s41467-021-24799-x2041-1723https://doaj.org/article/978a2efe63ee4aecbb0e7b5a78ffde382021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24799-xhttps://doaj.org/toc/2041-1723Autosomal dominant polycystic kidney disease is characterized by the formation of cysts in the kidney. Here the authors show that cystic extracellular vesicles/exosomes play a critical role in regulating the biology and function of adjacent cells, including renal epithelial cells, fibroblasts and macrophages, and contribute to renal cyst growth.Hao DingLinda Xiaoyan LiPeter C. HarrisJunwei YangXiaogang LiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hao Ding Linda Xiaoyan Li Peter C. Harris Junwei Yang Xiaogang Li Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease
description	Autosomal dominant polycystic kidney disease is characterized by the formation of cysts in the kidney. Here the authors show that cystic extracellular vesicles/exosomes play a critical role in regulating the biology and function of adjacent cells, including renal epithelial cells, fibroblasts and macrophages, and contribute to renal cyst growth.
format	article
author	Hao Ding Linda Xiaoyan Li Peter C. Harris Junwei Yang Xiaogang Li
author_facet	Hao Ding Linda Xiaoyan Li Peter C. Harris Junwei Yang Xiaogang Li
author_sort	Hao Ding
title	Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease
title_short	Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease
title_full	Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease
title_fullStr	Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease
title_full_unstemmed	Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease
title_sort	extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/978a2efe63ee4aecbb0e7b5a78ffde38
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Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease

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