Capturing transient antibody conformations with DNA origami epitopes

Understanding antibody-antigen interactions is important to deepen the understanding of immunology. Here, the authors report on the application of DNA origami structures for the controlled presentation of antigens to study antibody binding behaviours at room temperature.

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Autores principales:	Ping Zhang, Xiaoguo Liu, Pi Liu, Fei Wang, Hirotaka Ariyama, Toshio Ando, Jianping Lin, Lihua Wang, Jun Hu, Bin Li, Chunhai Fan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9790c451ed904099bfb8bd0d6eb1ee6a
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spelling	oai:doaj.org-article:9790c451ed904099bfb8bd0d6eb1ee6a2021-12-02T17:39:52ZCapturing transient antibody conformations with DNA origami epitopes10.1038/s41467-020-16949-42041-1723https://doaj.org/article/9790c451ed904099bfb8bd0d6eb1ee6a2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16949-4https://doaj.org/toc/2041-1723Understanding antibody-antigen interactions is important to deepen the understanding of immunology. Here, the authors report on the application of DNA origami structures for the controlled presentation of antigens to study antibody binding behaviours at room temperature.Ping ZhangXiaoguo LiuPi LiuFei WangHirotaka AriyamaToshio AndoJianping LinLihua WangJun HuBin LiChunhai FanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ping Zhang Xiaoguo Liu Pi Liu Fei Wang Hirotaka Ariyama Toshio Ando Jianping Lin Lihua Wang Jun Hu Bin Li Chunhai Fan Capturing transient antibody conformations with DNA origami epitopes
description	Understanding antibody-antigen interactions is important to deepen the understanding of immunology. Here, the authors report on the application of DNA origami structures for the controlled presentation of antigens to study antibody binding behaviours at room temperature.
format	article
author	Ping Zhang Xiaoguo Liu Pi Liu Fei Wang Hirotaka Ariyama Toshio Ando Jianping Lin Lihua Wang Jun Hu Bin Li Chunhai Fan
author_facet	Ping Zhang Xiaoguo Liu Pi Liu Fei Wang Hirotaka Ariyama Toshio Ando Jianping Lin Lihua Wang Jun Hu Bin Li Chunhai Fan
author_sort	Ping Zhang
title	Capturing transient antibody conformations with DNA origami epitopes
title_short	Capturing transient antibody conformations with DNA origami epitopes
title_full	Capturing transient antibody conformations with DNA origami epitopes
title_fullStr	Capturing transient antibody conformations with DNA origami epitopes
title_full_unstemmed	Capturing transient antibody conformations with DNA origami epitopes
title_sort	capturing transient antibody conformations with dna origami epitopes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/9790c451ed904099bfb8bd0d6eb1ee6a
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Capturing transient antibody conformations with DNA origami epitopes

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