Effectiveness of herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L in iron deficiency anemia patients

Objective: this study aimed to evaluate the effectiveness of herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L compared with iron supplement in Iron Deficiency Anemia (IDA) subjects. Materials and Methods: a total of 128 subjects with IDA were recruited and ra...

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Autores principales:	ULFA FITRIANI, zuraida zulkarnain, Fajar Novianto, Enggar Wijayanti, Agus Triyono
Formato:	article
Lenguaje:	EN
Publicado:	MBI & UNS Solo 2020
Materias:	amaranthus tricolor, curcuma zanthorrhiza, elephantopus scaber, iron deficiency anemia Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/97932b065d42490781dbbdc16f664c68
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spelling	oai:doaj.org-article:97932b065d42490781dbbdc16f664c682021-11-22T00:35:33ZEffectiveness of herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L in iron deficiency anemia patients1412-033X2085-472210.13057/biodiv/d210560https://doaj.org/article/97932b065d42490781dbbdc16f664c682020-05-01T00:00:00Zhttps://smujo.id/biodiv/article/view/5175https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Objective: this study aimed to evaluate the effectiveness of herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L compared with iron supplement in Iron Deficiency Anemia (IDA) subjects. Materials and Methods: a total of 128 subjects with IDA were recruited and randomly assigned to one of the two groups: Anemia herbs (AH) (n=64) and Iron supplement (IS) (n=64). The AH group received herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L two times daily and the IS group received Hufabion capsul for 4 weeks. Outcome measures were assesed 4 weeks after intervention. The outcomes of this study were hemoglobin (Hb), mean corpuscular volume (MCV), serum iron (SI), total iron banding capacity (TIBC) and quality of life (QOL) by using short form-36 (SF-36). Ethical Committee of NIHRD approval was obtained for this study. Results: A significant QOL effect in score of SF-36 of AH group was found after 4 weeks intervention (p<0,05). In contrast, no significant effect were found for the value of Hb, MCV , SI and TIBC (p>0,05) in the AH group. In the IS group, there were significant differences for value of Hb, MCV, SI, TIBC and SF-36 scores (p=0,000). Significant group effects were found for the value of Hb, MCV, SI and TIBC when comparing the IS group to AH group. There were also no significant differences between groups for QOL scores after 4 weeks intervention. Conclusion: Herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L proved to be an effective complementary therapy by improve QOL in the IDA patients.ULFA FITRIANIzuraida zulkarnainFajar NoviantoEnggar WijayantiAgus TriyonoMBI & UNS Soloarticleamaranthus tricolor, curcuma zanthorrhiza, elephantopus scaber, iron deficiency anemiaBiology (General)QH301-705.5ENBiodiversitas, Vol 21, Iss 5 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	amaranthus tricolor, curcuma zanthorrhiza, elephantopus scaber, iron deficiency anemia Biology (General) QH301-705.5
spellingShingle	amaranthus tricolor, curcuma zanthorrhiza, elephantopus scaber, iron deficiency anemia Biology (General) QH301-705.5 ULFA FITRIANI zuraida zulkarnain Fajar Novianto Enggar Wijayanti Agus Triyono Effectiveness of herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L in iron deficiency anemia patients
description	Objective: this study aimed to evaluate the effectiveness of herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L compared with iron supplement in Iron Deficiency Anemia (IDA) subjects. Materials and Methods: a total of 128 subjects with IDA were recruited and randomly assigned to one of the two groups: Anemia herbs (AH) (n=64) and Iron supplement (IS) (n=64). The AH group received herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L two times daily and the IS group received Hufabion capsul for 4 weeks. Outcome measures were assesed 4 weeks after intervention. The outcomes of this study were hemoglobin (Hb), mean corpuscular volume (MCV), serum iron (SI), total iron banding capacity (TIBC) and quality of life (QOL) by using short form-36 (SF-36). Ethical Committee of NIHRD approval was obtained for this study. Results: A significant QOL effect in score of SF-36 of AH group was found after 4 weeks intervention (p<0,05). In contrast, no significant effect were found for the value of Hb, MCV , SI and TIBC (p>0,05) in the AH group. In the IS group, there were significant differences for value of Hb, MCV, SI, TIBC and SF-36 scores (p=0,000). Significant group effects were found for the value of Hb, MCV, SI and TIBC when comparing the IS group to AH group. There were also no significant differences between groups for QOL scores after 4 weeks intervention. Conclusion: Herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L proved to be an effective complementary therapy by improve QOL in the IDA patients.
format	article
author	ULFA FITRIANI zuraida zulkarnain Fajar Novianto Enggar Wijayanti Agus Triyono
author_facet	ULFA FITRIANI zuraida zulkarnain Fajar Novianto Enggar Wijayanti Agus Triyono
author_sort	ULFA FITRIANI
title	Effectiveness of herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L in iron deficiency anemia patients
title_short	Effectiveness of herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L in iron deficiency anemia patients
title_full	Effectiveness of herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L in iron deficiency anemia patients
title_fullStr	Effectiveness of herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L in iron deficiency anemia patients
title_full_unstemmed	Effectiveness of herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L in iron deficiency anemia patients
title_sort	effectiveness of herbs containing curcuma xanthorrhiza, elephantopus scaber l and amaranthus tricolor l in iron deficiency anemia patients
publisher	MBI & UNS Solo
publishDate	2020
url	https://doaj.org/article/97932b065d42490781dbbdc16f664c68
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Effectiveness of herbs containing Curcuma xanthorrhiza, Elephantopus scaber L and Amaranthus tricolor L in iron deficiency anemia patients

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