Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe

Cholesterol influences membrane fluidity and forms membrane microdomains called lipid rafts that serve as organizing centers for the assembly of signaling molecules. Flotillin (FLOT) is a cholesterol-binding lipid-raft protein.

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Autores principales:	Weiyan Huang, Qingming Xiong, Mingqun Lin, Yasuko Rikihisa
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/9794048624f848c6a1bda52ff9429204
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spelling	oai:doaj.org-article:9794048624f848c6a1bda52ff94292042021-11-03T21:52:35ZAnaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe2150-751110.1128/mBio.02299-21https://doaj.org/article/9794048624f848c6a1bda52ff94292042021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02299-21https://doaj.org/toc/2150-7511 Cholesterol influences membrane fluidity and forms membrane microdomains called lipid rafts that serve as organizing centers for the assembly of signaling molecules. Flotillin (FLOT) is a cholesterol-binding lipid-raft protein.Weiyan HuangQingming XiongMingqun LinYasuko RikihisaAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Weiyan Huang Qingming Xiong Mingqun Lin Yasuko Rikihisa Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe
description	Cholesterol influences membrane fluidity and forms membrane microdomains called lipid rafts that serve as organizing centers for the assembly of signaling molecules. Flotillin (FLOT) is a cholesterol-binding lipid-raft protein.
format	article
author	Weiyan Huang Qingming Xiong Mingqun Lin Yasuko Rikihisa
author_facet	Weiyan Huang Qingming Xiong Mingqun Lin Yasuko Rikihisa
author_sort	Weiyan Huang
title	Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe
title_short	Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe
title_full	Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe
title_fullStr	Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe
title_full_unstemmed	Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe
title_sort	anaplasma phagocytophilum hijacks flotillin and npc1 complex to acquire intracellular cholesterol for proliferation, which can be inhibited with ezetimibe
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/9794048624f848c6a1bda52ff9429204
work_keys_str_mv	AT weiyanhuang anaplasmaphagocytophilumhijacksflotillinandnpc1complextoacquireintracellularcholesterolforproliferationwhichcanbeinhibitedwithezetimibe AT qingmingxiong anaplasmaphagocytophilumhijacksflotillinandnpc1complextoacquireintracellularcholesterolforproliferationwhichcanbeinhibitedwithezetimibe AT mingqunlin anaplasmaphagocytophilumhijacksflotillinandnpc1complextoacquireintracellularcholesterolforproliferationwhichcanbeinhibitedwithezetimibe AT yasukorikihisa anaplasmaphagocytophilumhijacksflotillinandnpc1complextoacquireintracellularcholesterolforproliferationwhichcanbeinhibitedwithezetimibe
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Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe

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