Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe

Cholesterol influences membrane fluidity and forms membrane microdomains called lipid rafts that serve as organizing centers for the assembly of signaling molecules. Flotillin (FLOT) is a cholesterol-binding lipid-raft protein.

Saved in:
Bibliographic Details
Main Authors: Weiyan Huang, Qingming Xiong, Mingqun Lin, Yasuko Rikihisa
Format: article
Language:EN
Published: American Society for Microbiology 2021
Subjects:
Online Access:https://doaj.org/article/9794048624f848c6a1bda52ff9429204
Tags: Add Tag
No Tags, Be the first to tag this record!