Eye muscle surgery for infantile nystagmus syndrome in the first two years of life

Richard W Hertle1, Joost Felius2, Dongsheng Yang1, Matthew Kaufman11The UPMC and Children&rsquo;s Hospital of Pittsburgh Eye Centers and The Laboratory of Visual and Ocular Motor Physiology Pittsburgh, PA, USA; 2The Retina Foundation of the Southwest, Department of Ophthalmology, University...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Richard W Hertle, Joost Felius, Dongsheng Yang, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2009
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/97a95c67ad094290bd9b5eaf1200bcec
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:97a95c67ad094290bd9b5eaf1200bcec
record_format	dspace
spelling	oai:doaj.org-article:97a95c67ad094290bd9b5eaf1200bcec2021-12-02T02:21:00ZEye muscle surgery for infantile nystagmus syndrome in the first two years of life1177-54671177-5483https://doaj.org/article/97a95c67ad094290bd9b5eaf1200bcec2009-11-01T00:00:00Zhttp://www.dovepress.com/eye-muscle-surgery-for-infantile-nystagmus-syndrome-in-the-first-two-y-a3700https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Richard W Hertle1, Joost Felius2, Dongsheng Yang1, Matthew Kaufman11The UPMC and Children&rsquo;s Hospital of Pittsburgh Eye Centers and The Laboratory of Visual and Ocular Motor Physiology Pittsburgh, PA, USA; 2The Retina Foundation of the Southwest, Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX, USAPurpose: To report visual and elctrophysioloigcal effects of eye muscle surgery in young patients with infantile nystagmus syndrome (INS).Methods: Prospective, interventional case cohort of 19 patients aged under 24 months who were operated on for combinations of strabismus, an anomalous head posture, and nystagmus. All patients were followed at least nine months. Outcome measures, part of an institutionally approved study, included Teller acuity, head position, strabismic deviation, and eye movement recordings, from which waveform types and a nystagmus optimal foveation fraction (NOFF). Computerized parametric and nonparametric statistical analysis of data were perfomed using standard software on both individual and group data.Results: Age averaged 17.7 months (13.1-month follow-up). Thirteen (68%) patients had associated optic nerve or retinal disease. 42% had amblyopia, 68% had refractive errors. Group means in binocular Teller acuity (P &lt; 0.05), strabismic deviation (P &lt; 0.05), head posture (P &lt; 0.001), and the NOFF measures (P &lt; 0.01) from eye movement recordings improved in all patients. There was a change in null zone waveforms to more favorable jerk types. There were no reoperations or surgical complications.Conclusions: Surgery on the extraocular muscles in patients aged less than two years with INS results in improvements in multiple aspects of ocular motor and visual function.Keywords: infantile nystagmus, anomalous head posture, eye muscle surgery Richard W HertleJoost FeliusDongsheng Yanget alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2009, Iss default, Pp 615-624 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Richard W Hertle Joost Felius Dongsheng Yang et al Eye muscle surgery for infantile nystagmus syndrome in the first two years of life
description	Richard W Hertle1, Joost Felius2, Dongsheng Yang1, Matthew Kaufman11The UPMC and Children&rsquo;s Hospital of Pittsburgh Eye Centers and The Laboratory of Visual and Ocular Motor Physiology Pittsburgh, PA, USA; 2The Retina Foundation of the Southwest, Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX, USAPurpose: To report visual and elctrophysioloigcal effects of eye muscle surgery in young patients with infantile nystagmus syndrome (INS).Methods: Prospective, interventional case cohort of 19 patients aged under 24 months who were operated on for combinations of strabismus, an anomalous head posture, and nystagmus. All patients were followed at least nine months. Outcome measures, part of an institutionally approved study, included Teller acuity, head position, strabismic deviation, and eye movement recordings, from which waveform types and a nystagmus optimal foveation fraction (NOFF). Computerized parametric and nonparametric statistical analysis of data were perfomed using standard software on both individual and group data.Results: Age averaged 17.7 months (13.1-month follow-up). Thirteen (68%) patients had associated optic nerve or retinal disease. 42% had amblyopia, 68% had refractive errors. Group means in binocular Teller acuity (P &lt; 0.05), strabismic deviation (P &lt; 0.05), head posture (P &lt; 0.001), and the NOFF measures (P &lt; 0.01) from eye movement recordings improved in all patients. There was a change in null zone waveforms to more favorable jerk types. There were no reoperations or surgical complications.Conclusions: Surgery on the extraocular muscles in patients aged less than two years with INS results in improvements in multiple aspects of ocular motor and visual function.Keywords: infantile nystagmus, anomalous head posture, eye muscle surgery
format	article
author	Richard W Hertle Joost Felius Dongsheng Yang et al
author_facet	Richard W Hertle Joost Felius Dongsheng Yang et al
author_sort	Richard W Hertle
title	Eye muscle surgery for infantile nystagmus syndrome in the first two years of life
title_short	Eye muscle surgery for infantile nystagmus syndrome in the first two years of life
title_full	Eye muscle surgery for infantile nystagmus syndrome in the first two years of life
title_fullStr	Eye muscle surgery for infantile nystagmus syndrome in the first two years of life
title_full_unstemmed	Eye muscle surgery for infantile nystagmus syndrome in the first two years of life
title_sort	eye muscle surgery for infantile nystagmus syndrome in the first two years of life
publisher	Dove Medical Press
publishDate	2009
url	https://doaj.org/article/97a95c67ad094290bd9b5eaf1200bcec
work_keys_str_mv	AT richardwhertle eyemusclesurgeryforinfantilenystagmussyndromeinthefirsttwoyearsoflife AT joostfelius eyemusclesurgeryforinfantilenystagmussyndromeinthefirsttwoyearsoflife AT dongshengyang eyemusclesurgeryforinfantilenystagmussyndromeinthefirsttwoyearsoflife AT etal eyemusclesurgeryforinfantilenystagmussyndromeinthefirsttwoyearsoflife
_version_	1718402543540764672

Eye muscle surgery for infantile nystagmus syndrome in the first two years of life

Ejemplares similares