Variant Aldehyde Dehydrogenase 2 (<i>ALDH2*2</i>) as a Risk Factor for Mechanical LA Substrate Formation and Atrial Fibrillation with Modest Alcohol Consumption in Ethnic Asians

Variant Aldehyde Dehydrogenase 2 (<i>ALDH2*2</i>) as a Risk Factor for Mechanical LA Substrate Formation and Atrial Fibrillation with Modest Alcohol Consumption in Ethnic Asians

Aldehyde dehydrogenase 2 (ALDH2) rs671 polymorphism is a common genetic variant in Asians that is responsible for defective toxic aldehyde and lipid peroxidation metabolism after alcohol consumption. The extent to which low alcohol consumption may cause atrial substrates to trigger atrial fibrillati...

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Main Authors: Chung-Lieh Hung, Kuo-Tzu Sung, Shun-Chuan Chang, Yen-Yu Liu, Jen-Yuan Kuo, Wen-Hung Huang, Cheng-Huang Su, Chuan-Chuan Liu, Shin-Yi Tsai, Chia-Yuan Liu, An-Sheng Lee, Szu-Hua Pan, Shih-Wei Wang, Charles Jia-Yin Hou, Ta-Chuan Hung, Hung-I Yeh
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
aldehyde dehydrogenase 2 (ALDH2)
alcohol
aldehyde
4-hydroxynonenal (4-HNE)
peak atrial longitudinal strain (PALS)
strain rates
Microbiology
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Online Access:https://doaj.org/article/97b4fcb1a4204bf69809b867b37e51db
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