Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis.

Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis.

<h4>Purpose</h4>Chronic Hepatitis C Virus (HCV)-infected patients with liver cirrhosis (LC) respond poorly to interferon-alpha (IFN-α) and ribavirin (RBV) combination therapy, but the reason for this is unclear. We previously reported that HCV-infection induces endoplasmic reticulum (ER)...

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Autores principales: Partha K Chandra, Feyza Gunduz, Sidhartha Hazari, Ramazan Kurt, Rajesh Panigrahi, Bret Poat, David Bruce, Ari J Cohen, Humberto E Bohorquez, Ian Carmody, George Loss, Luis A Balart, Tong Wu, Srikanta Dash
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/97b99bc571c9494aaab336ed28b36050
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