Prenatal hypoxia leads to hypertension, renal renin-angiotensin system activation and exacerbates salt-induced pathology in a sex-specific manner

Abstract Prenatal hypoxia is associated with growth restriction and adverse cardiovascular outcomes. Here, we describe renal and cardiovascular outcomes in ageing mouse offspring prenatally exposed to hypoxia (12% O2) from embryonic day 14.5 until birth. At 12 months of age, both male and female off...

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Autores principales: S. L. Walton, H. Bielefeldt-Ohmann, R. R. Singh, J. Li, T. M. Paravicini, M. H. Little, K. M. Moritz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/97cbf1cf9e1047368697e21dba9998c3
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