Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly

Ribosomes of all organisms have retained 5S rRNA as an autonomous rRNA species. Here the authors engineer a bacterial strain with ribosomes that do not have free 5S rRNA, and carry structural analyses that suggest the evolutionary preservation of 5S rRNA as an independent molecule is based on its ro...

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Autores principales:	Shijie Huang, Nikolay A. Aleksashin, Anna B. Loveland, Dorota Klepacki, Kaspar Reier, Amira Kefi, Teresa Szal, Jaanus Remme, Luc Jaeger, Nora Vázquez-Laslop, Andrei A. Korostelev, Alexander S. Mankin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/97ce74dddff14abd9b4d20a9c96f526d
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spelling	oai:doaj.org-article:97ce74dddff14abd9b4d20a9c96f526d2021-12-02T17:52:09ZRibosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly10.1038/s41467-020-16694-82041-1723https://doaj.org/article/97ce74dddff14abd9b4d20a9c96f526d2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16694-8https://doaj.org/toc/2041-1723Ribosomes of all organisms have retained 5S rRNA as an autonomous rRNA species. Here the authors engineer a bacterial strain with ribosomes that do not have free 5S rRNA, and carry structural analyses that suggest the evolutionary preservation of 5S rRNA as an independent molecule is based on its role in the dynamic process of ribosome biogenesis.Shijie HuangNikolay A. AleksashinAnna B. LovelandDorota KlepackiKaspar ReierAmira KefiTeresa SzalJaanus RemmeLuc JaegerNora Vázquez-LaslopAndrei A. KorostelevAlexander S. MankinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shijie Huang Nikolay A. Aleksashin Anna B. Loveland Dorota Klepacki Kaspar Reier Amira Kefi Teresa Szal Jaanus Remme Luc Jaeger Nora Vázquez-Laslop Andrei A. Korostelev Alexander S. Mankin Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly
description	Ribosomes of all organisms have retained 5S rRNA as an autonomous rRNA species. Here the authors engineer a bacterial strain with ribosomes that do not have free 5S rRNA, and carry structural analyses that suggest the evolutionary preservation of 5S rRNA as an independent molecule is based on its role in the dynamic process of ribosome biogenesis.
format	article
author	Shijie Huang Nikolay A. Aleksashin Anna B. Loveland Dorota Klepacki Kaspar Reier Amira Kefi Teresa Szal Jaanus Remme Luc Jaeger Nora Vázquez-Laslop Andrei A. Korostelev Alexander S. Mankin
author_facet	Shijie Huang Nikolay A. Aleksashin Anna B. Loveland Dorota Klepacki Kaspar Reier Amira Kefi Teresa Szal Jaanus Remme Luc Jaeger Nora Vázquez-Laslop Andrei A. Korostelev Alexander S. Mankin
author_sort	Shijie Huang
title	Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly
title_short	Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly
title_full	Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly
title_fullStr	Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly
title_full_unstemmed	Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly
title_sort	ribosome engineering reveals the importance of 5s rrna autonomy for ribosome assembly
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/97ce74dddff14abd9b4d20a9c96f526d
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Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly

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