Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly
Ribosomes of all organisms have retained 5S rRNA as an autonomous rRNA species. Here the authors engineer a bacterial strain with ribosomes that do not have free 5S rRNA, and carry structural analyses that suggest the evolutionary preservation of 5S rRNA as an independent molecule is based on its ro...
Enregistré dans:
Auteurs principaux: | Shijie Huang, Nikolay A. Aleksashin, Anna B. Loveland, Dorota Klepacki, Kaspar Reier, Amira Kefi, Teresa Szal, Jaanus Remme, Luc Jaeger, Nora Vázquez-Laslop, Andrei A. Korostelev, Alexander S. Mankin |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/97ce74dddff14abd9b4d20a9c96f526d |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Assembly and functionality of the ribosome with tethered subunits
par: Nikolay A. Aleksashin, et autres
Publié: (2019) -
Context-specific action of macrolide antibiotics on the eukaryotic ribosome
par: Maxim S. Svetlov, et autres
Publié: (2021) -
Engineered ribosomes with tethered subunits for expanding biological function
par: Erik D. Carlson, et autres
Publié: (2019) -
Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation
par: Gabriel Demo, et autres
Publié: (2021) -
Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling
par: Anne-Xander van der Stel, et autres
Publié: (2021)