Tunable heat shock protein-mediated NK cell responses are orchestrated by STAT1 in Antigen Presenting Cells

Abstract The release of Heat Shock Proteins (HSPs) from aberrant cells can initiate immune responses following engagement of the HSPs with antigen presenting cells (APCs). This is an important mechanism for cancer immunosurveillance and can also be modeled by vaccination with HSPs through various ro...

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Autores principales: Abigail L. Sedlacek, Lauren B. Kinner-Bibeau, Yifei Wang, Alicia P. Mizes, Robert J. Binder
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/97d4f75192d24757a9d884d4ad3eb92d
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