Role of AmpR in the High Expression of the Plasmid-Encoded AmpC β-Lactamase CFE-1

ABSTRACT CFE-1 is a unique plasmid-encoded AmpC β-lactamase with the regulator gene ampR. It imparts high resistance to most cephalosporins with constitutive high-level β-lactamase activity. Here, the β-lactamase activities and expression levels of ampC with or without ampR were investigated. Result...

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Bibliographic Details
Main Authors: Ryuichi Nakano, Akiyo Nakano, Hisakazu Yano, Ryoichi Okamoto
Format: article
Language:EN
Published: American Society for Microbiology 2017
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Online Access:https://doaj.org/article/97d56aac9fb84060bedb3085d6093c89
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