The effects of in-hospital deprescribing on potential prescribing omission in hospitalized elderly patients with polypharmacy

Abstract No studies to investigate the effect of a deprescribing intervention on the occurrence of potential prescribing omissions (PPOs) among elderly patients with polypharmacy have been conducted. Therefore, the effect of deprescribing on PPOs among elderly patients with polypharmacy was investig...

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Autores principales:	Miho Kaminaga, Junpei Komagamine, Shinpei Tatsumi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/97e2d9daf3264ca08b36755ce1e45b9d
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spelling	oai:doaj.org-article:97e2d9daf3264ca08b36755ce1e45b9d2021-12-02T16:55:54ZThe effects of in-hospital deprescribing on potential prescribing omission in hospitalized elderly patients with polypharmacy10.1038/s41598-021-88362-w2045-2322https://doaj.org/article/97e2d9daf3264ca08b36755ce1e45b9d2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-88362-whttps://doaj.org/toc/2045-2322Abstract No studies to investigate the effect of a deprescribing intervention on the occurrence of potential prescribing omissions (PPOs) among elderly patients with polypharmacy have been conducted. Therefore, the effect of deprescribing on PPOs among elderly patients with polypharmacy was investigated. All 121 consecutive elderly patients who received in-hospital deprescribing interventions were evaluated. The primary outcome was any occurrence of PPOs based on the 2015 STOPP/START criteria. The proportion of patients who had any PPOs significantly increased after the deprescribing interventions (52.9% vs 77.7%, p < 0.001). In the multivariable analysis, older age was the only independent risk factor associated with an increased risk of any PPOs after the deprescribing interventions (OR 1.08, 95% CI 1.01 to 1.16). In-hospital deprescribing interventions for elderly patients with polypharmacy may increase the occurrence of PPOs. Further study is warranted to investigate the effects on clinical outcomes of the increased occurrence of PPOs due to the deprescribing intervention.Miho KaminagaJunpei KomagamineShinpei TatsumiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Miho Kaminaga Junpei Komagamine Shinpei Tatsumi The effects of in-hospital deprescribing on potential prescribing omission in hospitalized elderly patients with polypharmacy
description	Abstract No studies to investigate the effect of a deprescribing intervention on the occurrence of potential prescribing omissions (PPOs) among elderly patients with polypharmacy have been conducted. Therefore, the effect of deprescribing on PPOs among elderly patients with polypharmacy was investigated. All 121 consecutive elderly patients who received in-hospital deprescribing interventions were evaluated. The primary outcome was any occurrence of PPOs based on the 2015 STOPP/START criteria. The proportion of patients who had any PPOs significantly increased after the deprescribing interventions (52.9% vs 77.7%, p < 0.001). In the multivariable analysis, older age was the only independent risk factor associated with an increased risk of any PPOs after the deprescribing interventions (OR 1.08, 95% CI 1.01 to 1.16). In-hospital deprescribing interventions for elderly patients with polypharmacy may increase the occurrence of PPOs. Further study is warranted to investigate the effects on clinical outcomes of the increased occurrence of PPOs due to the deprescribing intervention.
format	article
author	Miho Kaminaga Junpei Komagamine Shinpei Tatsumi
author_facet	Miho Kaminaga Junpei Komagamine Shinpei Tatsumi
author_sort	Miho Kaminaga
title	The effects of in-hospital deprescribing on potential prescribing omission in hospitalized elderly patients with polypharmacy
title_short	The effects of in-hospital deprescribing on potential prescribing omission in hospitalized elderly patients with polypharmacy
title_full	The effects of in-hospital deprescribing on potential prescribing omission in hospitalized elderly patients with polypharmacy
title_fullStr	The effects of in-hospital deprescribing on potential prescribing omission in hospitalized elderly patients with polypharmacy
title_full_unstemmed	The effects of in-hospital deprescribing on potential prescribing omission in hospitalized elderly patients with polypharmacy
title_sort	effects of in-hospital deprescribing on potential prescribing omission in hospitalized elderly patients with polypharmacy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/97e2d9daf3264ca08b36755ce1e45b9d
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The effects of in-hospital deprescribing on potential prescribing omission in hospitalized elderly patients with polypharmacy

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