COVID-19 and the Gut Microbiome: More than a Gut Feeling

ABSTRACT Due to its fundamental role in the induction, training, and function of the immune system, it is critical to include characterizations of the gut microbiome in clinical trials and studies that aim to broaden our understanding of coronavirus disease 2019 (COVID-19). Understanding the “gut-lu...

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Autores principales:	Daniel van der Lelie, Safiyh Taghavi
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2020
Materias:	COVID-19 gut microbiome Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/97e3335697904c2e944fee70016245da
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spelling	oai:doaj.org-article:97e3335697904c2e944fee70016245da2021-12-02T19:46:20ZCOVID-19 and the Gut Microbiome: More than a Gut Feeling10.1128/mSystems.00453-202379-5077https://doaj.org/article/97e3335697904c2e944fee70016245da2020-08-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00453-20https://doaj.org/toc/2379-5077ABSTRACT Due to its fundamental role in the induction, training, and function of the immune system, it is critical to include characterizations of the gut microbiome in clinical trials and studies that aim to broaden our understanding of coronavirus disease 2019 (COVID-19). Understanding the “gut-lung axes,” where gut microbiome composition influences the lung’s susceptibility to viral infections and viral infections of the lung alter gut microbiome composition toward proinflammatory functional dysbiosis, will be critical in addressing COVID-19, including disease progression, the importance of preexisting conditions, and the risk for developing complications. These insights may further help to develop better intervention strategies for COVID-19 and other diseases caused by respiratory viruses.Daniel van der LelieSafiyh TaghaviAmerican Society for MicrobiologyarticleCOVID-19gut microbiomeMicrobiologyQR1-502ENmSystems, Vol 5, Iss 4 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 gut microbiome Microbiology QR1-502
spellingShingle	COVID-19 gut microbiome Microbiology QR1-502 Daniel van der Lelie Safiyh Taghavi COVID-19 and the Gut Microbiome: More than a Gut Feeling
description	ABSTRACT Due to its fundamental role in the induction, training, and function of the immune system, it is critical to include characterizations of the gut microbiome in clinical trials and studies that aim to broaden our understanding of coronavirus disease 2019 (COVID-19). Understanding the “gut-lung axes,” where gut microbiome composition influences the lung’s susceptibility to viral infections and viral infections of the lung alter gut microbiome composition toward proinflammatory functional dysbiosis, will be critical in addressing COVID-19, including disease progression, the importance of preexisting conditions, and the risk for developing complications. These insights may further help to develop better intervention strategies for COVID-19 and other diseases caused by respiratory viruses.
format	article
author	Daniel van der Lelie Safiyh Taghavi
author_facet	Daniel van der Lelie Safiyh Taghavi
author_sort	Daniel van der Lelie
title	COVID-19 and the Gut Microbiome: More than a Gut Feeling
title_short	COVID-19 and the Gut Microbiome: More than a Gut Feeling
title_full	COVID-19 and the Gut Microbiome: More than a Gut Feeling
title_fullStr	COVID-19 and the Gut Microbiome: More than a Gut Feeling
title_full_unstemmed	COVID-19 and the Gut Microbiome: More than a Gut Feeling
title_sort	covid-19 and the gut microbiome: more than a gut feeling
publisher	American Society for Microbiology
publishDate	2020
url	https://doaj.org/article/97e3335697904c2e944fee70016245da
work_keys_str_mv	AT danielvanderlelie covid19andthegutmicrobiomemorethanagutfeeling AT safiyhtaghavi covid19andthegutmicrobiomemorethanagutfeeling
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COVID-19 and the Gut Microbiome: More than a Gut Feeling

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