Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion

Myoblast fusion is an essential step in muscle growth and regeneration, and is regulated by the G-protein coupled receptor (GPCR) BAI3. Here Hamoud et al. show that the GPCR activity of BAI3 is spatiotemporally regulated during myoblast fusion, and identify C1qL4 and Stabilin-2 as, respectively, neg...

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Autores principales:	Noumeira Hamoud, Viviane Tran, Takahiro Aimi, Wataru Kakegawa, Sylvie Lahaie, Marie-Pier Thibault, Ariane Pelletier, G. William Wong, In-San Kim, Artur Kania, Michisuke Yuzaki, Michel Bouvier, Jean-François Côté
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/97e34f01ba7746fbbf62f89e3ee24f73
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spelling	oai:doaj.org-article:97e34f01ba7746fbbf62f89e3ee24f732021-12-02T14:39:25ZSpatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion10.1038/s41467-018-06897-52041-1723https://doaj.org/article/97e34f01ba7746fbbf62f89e3ee24f732018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06897-5https://doaj.org/toc/2041-1723Myoblast fusion is an essential step in muscle growth and regeneration, and is regulated by the G-protein coupled receptor (GPCR) BAI3. Here Hamoud et al. show that the GPCR activity of BAI3 is spatiotemporally regulated during myoblast fusion, and identify C1qL4 and Stabilin-2 as, respectively, negative and positive regulators of its activity.Noumeira HamoudViviane TranTakahiro AimiWataru KakegawaSylvie LahaieMarie-Pier ThibaultAriane PelletierG. William WongIn-San KimArtur KaniaMichisuke YuzakiMichel BouvierJean-François CôtéNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Noumeira Hamoud Viviane Tran Takahiro Aimi Wataru Kakegawa Sylvie Lahaie Marie-Pier Thibault Ariane Pelletier G. William Wong In-San Kim Artur Kania Michisuke Yuzaki Michel Bouvier Jean-François Côté Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion
description	Myoblast fusion is an essential step in muscle growth and regeneration, and is regulated by the G-protein coupled receptor (GPCR) BAI3. Here Hamoud et al. show that the GPCR activity of BAI3 is spatiotemporally regulated during myoblast fusion, and identify C1qL4 and Stabilin-2 as, respectively, negative and positive regulators of its activity.
format	article
author	Noumeira Hamoud Viviane Tran Takahiro Aimi Wataru Kakegawa Sylvie Lahaie Marie-Pier Thibault Ariane Pelletier G. William Wong In-San Kim Artur Kania Michisuke Yuzaki Michel Bouvier Jean-François Côté
author_facet	Noumeira Hamoud Viviane Tran Takahiro Aimi Wataru Kakegawa Sylvie Lahaie Marie-Pier Thibault Ariane Pelletier G. William Wong In-San Kim Artur Kania Michisuke Yuzaki Michel Bouvier Jean-François Côté
author_sort	Noumeira Hamoud
title	Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion
title_short	Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion
title_full	Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion
title_fullStr	Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion
title_full_unstemmed	Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion
title_sort	spatiotemporal regulation of the gpcr activity of bai3 by c1ql4 and stabilin-2 controls myoblast fusion
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/97e34f01ba7746fbbf62f89e3ee24f73
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Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion

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