In vitro study of novel collagenase (XIAFLEX®) on Dupuytren's disease fibroblasts displays unique drug related properties.

Dupuytren's disease (DD) is a benign, fibroproliferative disease of the palmar fascia, with excessive extracellular matrix (ECM) deposition and over-production of cytokines and growth factors, resulting in digital fixed flexion contractures limiting hand function and patient quality of life. Su...

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Autores principales: Farhatullah Syed, Alexis N Thomas, Subir Singh, Venkatesh Kolluru, Susan G Emeigh Hart, Ardeshir Bayat
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/97f76caf62034bed873be8847ebc93aa
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