Genomic runs of homozygosity record population history and consanguinity.

The human genome is characterised by many runs of homozygous genotypes, where identical haplotypes were inherited from each parent. The length of each run is determined partly by the number of generations since the common ancestor: offspring of cousin marriages have long runs of homozygosity (ROH),...

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Autores principales: Mirna Kirin, Ruth McQuillan, Christopher S Franklin, Harry Campbell, Paul M McKeigue, James F Wilson
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/97fc13310262473f87ef596312f05c6e
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