A Low-Producing Haplotype of Interleukin-6 Disrupting CTCF Binding Is Protective against Severe COVID-19

A Low-Producing Haplotype of Interleukin-6 Disrupting CTCF Binding Is Protective against Severe COVID-19

Overproduction of cytokine interleukin-6 (IL-6) is a hallmark of severe COVID-19 and is believed to play a critical role in exacerbating the excessive inflammatory response. Polymorphisms in IL-6

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Autores principales: Tao Chen, Yu-Xin Lin, Yan Zha, Ying Sun, Jinxiu Tian, Zhiying Yang, Shan-Wen Lin, Fuxun Yu, Zi-Sheng Chen, Bo-Hua Kuang, Jin-Ju Lei, Ying-jie Nie, Yonghao Xu, Dong-Bo Tian, Ying-Zi Li, Bin Yang, Qiang Xu, Li Yang, Nanshan Zhong, Meizhen Zheng, Yimin Li, Jincun Zhao, Xiang-Yan Zhang, Lin Feng
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/97fc514b23474874a78ba95c85b85b89
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