Extra virgin olive oil improved body weight and insulin sensitivity in high fat diet-induced obese LDLr−/−.Leiden mice without attenuation of steatohepatitis

Extra virgin olive oil improved body weight and insulin sensitivity in high fat diet-induced obese LDLr−/−.Leiden mice without attenuation of steatohepatitis

Abstract Dietary fatty acids play a role in the pathogenesis of obesity-associated non-alcoholic fatty liver disease (NAFLD), which is associated with insulin resistance (IR). Fatty acid composition is critical for IR and subsequent NAFLD development. Extra-virgin olive oil (EVOO) is the main source...

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Main Authors: Leticia Álvarez-Amor, Amparo Luque Sierra, Antonio Cárdenas, Lucía López-Bermudo, Javier López-Beas, Eloísa Andújar, Mónica Pérez-Alegre, Rocío Gallego-Durán, Lourdes M. Varela, Alejandro Martin-Montalvo, Genoveva Berná, Anabel Rojas, Mª José Robles-Frías, Abdelkrim Hmadcha, Manuel Romero-Gómez, Robert Kleemann, Franz Martín
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/98018cb0ec61418692f64df0f9c6509c
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https://doaj.org/article/98018cb0ec61418692f64df0f9c6509c

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