Hit-and-run programming of therapeutic cytoreagents using mRNA nanocarriers

Hit-and-run programming of therapeutic cytoreagents using mRNA nanocarriers

Current widely used viral and electroporation methods for creating therapeutic cell-based products are complex and expensive. Here, the authors develop targeted mRNA nanocarriers that can transiently program gene expression by simply mixing them with cells, to improve their therapeutic potential.

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Detalles Bibliográficos
Autores principales: H. F. Moffett, M. E. Coon, S. Radtke, S. B. Stephan, L. McKnight, A. Lambert, B. L. Stoddard, H. P. Kiem, M. T. Stephan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
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Acceso en línea:https://doaj.org/article/980299c002f4470893064c45e6cc2b18
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