Randomized controlled clinical trial on bleaching sensitivity and whitening efficacy of hydrogen peroxide versus combinations of hydrogen peroxide and ozone

Abstract The clinical efficacy regarding bleaching sensitivity and tooth shade lightening using a standard hydrogen peroxide (H2O2) bleaching gel was compared with the additional use of ozone either before or after application of H2O2. Using computer-generated tables, 45 participants were randomly a...

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Autores principales:	Mahmoud K. AL-Omiri, Abdullah A. Al Nazeh, Andrej M. Kielbassa, Edward Lynch
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/980d280da92647509d5906d51343558e
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spelling	oai:doaj.org-article:980d280da92647509d5906d51343558e2021-12-02T11:41:24ZRandomized controlled clinical trial on bleaching sensitivity and whitening efficacy of hydrogen peroxide versus combinations of hydrogen peroxide and ozone10.1038/s41598-018-20878-02045-2322https://doaj.org/article/980d280da92647509d5906d51343558e2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-20878-0https://doaj.org/toc/2045-2322Abstract The clinical efficacy regarding bleaching sensitivity and tooth shade lightening using a standard hydrogen peroxide (H2O2) bleaching gel was compared with the additional use of ozone either before or after application of H2O2. Using computer-generated tables, 45 participants were randomly allocated into three groups (n = 15 each) in this investigator-driven, single-centre trial. In Group 1, upper anterior teeth were bleached using ozone (produced via a healOzone X4 device) for 60 seconds, then 38% H2O2 for 20 minutes; in Group 2, 38% H2O2 application (20 min) was followed by ozone (60 s); air produced by the healOzone machine (60 s) followed by 38% H2O2 (20 min) was used in Group 3 (control). Bleaching sensitivity was evaluated via visual analogue scales, and a treatment-blinded reader objectively recorded tooth shades using a colorimeter before and 24 hours after bleaching (at α = 0.05). The H2O2/ozone combination did not result in pain sensations, while both ozone/H2O2 and H2O2 alone increased bleaching sensitivity (p < 0.001). Teeth achieved lighter shades (higher L/lower b values) after bleaching in all groups (p < 0.001), while Ozone boosted lighter tooth shades, irrespective of its use before or after H2O2 (p < 0.05). Due to the complimentary effects, applying ozone after H2O2 seems preferable for bleaching.Mahmoud K. AL-OmiriAbdullah A. Al NazehAndrej M. KielbassaEdward LynchNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mahmoud K. AL-Omiri Abdullah A. Al Nazeh Andrej M. Kielbassa Edward Lynch Randomized controlled clinical trial on bleaching sensitivity and whitening efficacy of hydrogen peroxide versus combinations of hydrogen peroxide and ozone
description	Abstract The clinical efficacy regarding bleaching sensitivity and tooth shade lightening using a standard hydrogen peroxide (H2O2) bleaching gel was compared with the additional use of ozone either before or after application of H2O2. Using computer-generated tables, 45 participants were randomly allocated into three groups (n = 15 each) in this investigator-driven, single-centre trial. In Group 1, upper anterior teeth were bleached using ozone (produced via a healOzone X4 device) for 60 seconds, then 38% H2O2 for 20 minutes; in Group 2, 38% H2O2 application (20 min) was followed by ozone (60 s); air produced by the healOzone machine (60 s) followed by 38% H2O2 (20 min) was used in Group 3 (control). Bleaching sensitivity was evaluated via visual analogue scales, and a treatment-blinded reader objectively recorded tooth shades using a colorimeter before and 24 hours after bleaching (at α = 0.05). The H2O2/ozone combination did not result in pain sensations, while both ozone/H2O2 and H2O2 alone increased bleaching sensitivity (p < 0.001). Teeth achieved lighter shades (higher L/lower b values) after bleaching in all groups (p < 0.001), while Ozone boosted lighter tooth shades, irrespective of its use before or after H2O2 (p < 0.05). Due to the complimentary effects, applying ozone after H2O2 seems preferable for bleaching.
format	article
author	Mahmoud K. AL-Omiri Abdullah A. Al Nazeh Andrej M. Kielbassa Edward Lynch
author_facet	Mahmoud K. AL-Omiri Abdullah A. Al Nazeh Andrej M. Kielbassa Edward Lynch
author_sort	Mahmoud K. AL-Omiri
title	Randomized controlled clinical trial on bleaching sensitivity and whitening efficacy of hydrogen peroxide versus combinations of hydrogen peroxide and ozone
title_short	Randomized controlled clinical trial on bleaching sensitivity and whitening efficacy of hydrogen peroxide versus combinations of hydrogen peroxide and ozone
title_full	Randomized controlled clinical trial on bleaching sensitivity and whitening efficacy of hydrogen peroxide versus combinations of hydrogen peroxide and ozone
title_fullStr	Randomized controlled clinical trial on bleaching sensitivity and whitening efficacy of hydrogen peroxide versus combinations of hydrogen peroxide and ozone
title_full_unstemmed	Randomized controlled clinical trial on bleaching sensitivity and whitening efficacy of hydrogen peroxide versus combinations of hydrogen peroxide and ozone
title_sort	randomized controlled clinical trial on bleaching sensitivity and whitening efficacy of hydrogen peroxide versus combinations of hydrogen peroxide and ozone
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/980d280da92647509d5906d51343558e
work_keys_str_mv	AT mahmoudkalomiri randomizedcontrolledclinicaltrialonbleachingsensitivityandwhiteningefficacyofhydrogenperoxideversuscombinationsofhydrogenperoxideandozone AT abdullahaalnazeh randomizedcontrolledclinicaltrialonbleachingsensitivityandwhiteningefficacyofhydrogenperoxideversuscombinationsofhydrogenperoxideandozone AT andrejmkielbassa randomizedcontrolledclinicaltrialonbleachingsensitivityandwhiteningefficacyofhydrogenperoxideversuscombinationsofhydrogenperoxideandozone AT edwardlynch randomizedcontrolledclinicaltrialonbleachingsensitivityandwhiteningefficacyofhydrogenperoxideversuscombinationsofhydrogenperoxideandozone
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Randomized controlled clinical trial on bleaching sensitivity and whitening efficacy of hydrogen peroxide versus combinations of hydrogen peroxide and ozone

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