Isoliquiritigenin attenuates acute renal injury through suppressing oxidative stress, fibrosis and JAK2/STAT3 pathway in streptozotocin-induced diabetic rats
The aim of the current study was to evaluate the protective effects and mechanisms of isoliquiritigenin (ISO) on acute renal injury. CCK-8 assays were applied to assess the effects of ISO at different doses (20, 40, and 80 μg/mL) on oxidative damage in human renal HK-2 cells incubated with high gluc...
Guardado en:
Autores principales: | Leiming Sun, Zheng Yang, Jiaying Zhang, Jie Wang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Taylor & Francis Group
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/980eb883e6384058b018ed173c5166b1 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Silica nanoparticles induce liver fibrosis via TGF-β1/Smad3 pathway in ICR mice
por: Yu Y, et al.
Publicado: (2017) -
Curdione and Schisandrin C Synergistically Reverse Hepatic Fibrosis via Modulating the TGF-β Pathway and Inhibiting Oxidative Stress
por: Wenzhang Dai, et al.
Publicado: (2021) -
Repeated intravenous administration of silica nanoparticles induces pulmonary inflammation and collagen accumulation via JAK2/STAT3 and TGF-β/Smad3 pathways in vivo
por: Yu Y, et al.
Publicado: (2019) -
Integrin β3 Induction Promotes Tubular Cell Senescence and Kidney Fibrosis
por: Shen Li, et al.
Publicado: (2021) -
GPR37 promotes the malignancy of lung adenocarcinoma via TGF-β/Smad pathway
por: Wang Jian, et al.
Publicado: (2020)