Bacterial polyphosphates interfere with the innate host defense to infection

Bacterial polyphosphates interfere with the innate host defense to infection

Production of polyphosphate polymers is a ubiquitous trait of bacteria. Here, the authors investigate the role of bacterial long polyphosphates in host immune suppression and show that long polyphosphates produced by E. coli inhibit LPS-mediated inflammation and bacterial clearance in mice.

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Bibliographic Details
Main Authors: Julian Roewe, Georgios Stavrides, Marcel Strueve, Arjun Sharma, Federico Marini, Amrit Mann, Stephanie A. Smith, Ziya Kaya, Birgit Strobl, Mathias Mueller, Christoph Reinhardt, James H. Morrissey, Markus Bosmann
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Science
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Online Access:https://doaj.org/article/981bd424c2f4496e8c311fc4f1a08f66
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Internet

https://doaj.org/article/981bd424c2f4496e8c311fc4f1a08f66

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