Cwp19 Is a Novel Lytic Transglycosylase Involved in Stationary-Phase Autolysis Resulting in Toxin Release in <italic toggle="yes">Clostridium difficile</italic>

ABSTRACT Clostridium difficile is the major etiologic agent of antibiotic-associated intestinal disease. Pathogenesis of C. difficile is mainly attributed to the production and secretion of toxins A and B. Unlike most clostridial toxins, toxins A and B have no signal peptide, and they are therefore...

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Main Authors: Sandra Wydau-Dematteis, Imane El Meouche, Pascal Courtin, Audrey Hamiot, René Lai-Kuen, Bruno Saubaméa, François Fenaille, Marie-José Butel, Jean-Louis Pons, Bruno Dupuy, Marie-Pierre Chapot-Chartier, Johann Peltier
Format: article
Language:EN
Published: American Society for Microbiology 2018
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Online Access:https://doaj.org/article/981e2cb1b5b04f1781907b9a09bd4184
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