Consensus Guidelines for Improving Quality of Assessment and Training for Neuromuscular Diseases

Critical components of successful evaluation of clinical outcome assessments (COAs) in multisite clinical trials and clinical practice are standardized training, administration, and documented reliability of scoring. Experiences of evaluators, alongside patient differences from regional standards of...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Tina Duong, Kristin J. Krosschell, Meredith K. James, Leslie Nelson, Lindsay N. Alfano, Katy Eichinger, Elena Mazzone, Kristy Rose, Linda P. Lowes, Anna Mayhew, Julaine Florence, Wendy King, Claudia R. Senesac, Michelle Eagle
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	clinical outcomes assessment clinical evaluation education neuromuscular disease (NMD) evaluator training clinical trial readiness Genetics QH426-470
Acceso en línea:	https://doaj.org/article/981e516b28d04a8384a87ee77f7b25aa
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:981e516b28d04a8384a87ee77f7b25aa
record_format	dspace
spelling	oai:doaj.org-article:981e516b28d04a8384a87ee77f7b25aa2021-11-10T08:26:58ZConsensus Guidelines for Improving Quality of Assessment and Training for Neuromuscular Diseases1664-802110.3389/fgene.2021.735936https://doaj.org/article/981e516b28d04a8384a87ee77f7b25aa2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fgene.2021.735936/fullhttps://doaj.org/toc/1664-8021Critical components of successful evaluation of clinical outcome assessments (COAs) in multisite clinical trials and clinical practice are standardized training, administration, and documented reliability of scoring. Experiences of evaluators, alongside patient differences from regional standards of care, may contribute to heterogeneity in clinical center’s expertise. Achieving low variability and high reliability of COA is fundamental to clinical research and to give confidence in our ability to draw rational, interpretable conclusions from the data collected. The objective of this manuscript is to provide a framework to guide the learning process for COAs for use in clinics and clinical trials to maximize reliability and validity of COAs in neuromuscular disease (NMD). This is a consensus-based guideline with contributions from fourteen leading experts in clinical outcomes and the field of clinical outcome training in NMD. This framework should guide reliable and valid assessments in NMD specialty clinics and clinical trials. This consensus aims to expedite study start up with a progressive training pathway ranging from research naïve to highly experienced clinical evaluators. This document includes recommendations for education guidelines and roles and responsibilities of key stakeholders in COA assessment and implementation to ensure quality and consistency of outcome administration across different settings.Tina DuongTina DuongKristin J. KrosschellMeredith K. JamesLeslie NelsonLindsay N. AlfanoLindsay N. AlfanoKaty EichingerElena MazzoneKristy RoseLinda P. LowesLinda P. LowesAnna MayhewJulaine FlorenceWendy KingClaudia R. SenesacMichelle EagleMichelle EagleFrontiers Media S.A.articleclinical outcomes assessmentclinical evaluation educationneuromuscular disease (NMD)evaluator trainingclinical trial readinessGeneticsQH426-470ENFrontiers in Genetics, Vol 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	clinical outcomes assessment clinical evaluation education neuromuscular disease (NMD) evaluator training clinical trial readiness Genetics QH426-470
spellingShingle	clinical outcomes assessment clinical evaluation education neuromuscular disease (NMD) evaluator training clinical trial readiness Genetics QH426-470 Tina Duong Tina Duong Kristin J. Krosschell Meredith K. James Leslie Nelson Lindsay N. Alfano Lindsay N. Alfano Katy Eichinger Elena Mazzone Kristy Rose Linda P. Lowes Linda P. Lowes Anna Mayhew Julaine Florence Wendy King Claudia R. Senesac Michelle Eagle Michelle Eagle Consensus Guidelines for Improving Quality of Assessment and Training for Neuromuscular Diseases
description	Critical components of successful evaluation of clinical outcome assessments (COAs) in multisite clinical trials and clinical practice are standardized training, administration, and documented reliability of scoring. Experiences of evaluators, alongside patient differences from regional standards of care, may contribute to heterogeneity in clinical center’s expertise. Achieving low variability and high reliability of COA is fundamental to clinical research and to give confidence in our ability to draw rational, interpretable conclusions from the data collected. The objective of this manuscript is to provide a framework to guide the learning process for COAs for use in clinics and clinical trials to maximize reliability and validity of COAs in neuromuscular disease (NMD). This is a consensus-based guideline with contributions from fourteen leading experts in clinical outcomes and the field of clinical outcome training in NMD. This framework should guide reliable and valid assessments in NMD specialty clinics and clinical trials. This consensus aims to expedite study start up with a progressive training pathway ranging from research naïve to highly experienced clinical evaluators. This document includes recommendations for education guidelines and roles and responsibilities of key stakeholders in COA assessment and implementation to ensure quality and consistency of outcome administration across different settings.
format	article
author	Tina Duong Tina Duong Kristin J. Krosschell Meredith K. James Leslie Nelson Lindsay N. Alfano Lindsay N. Alfano Katy Eichinger Elena Mazzone Kristy Rose Linda P. Lowes Linda P. Lowes Anna Mayhew Julaine Florence Wendy King Claudia R. Senesac Michelle Eagle Michelle Eagle
author_facet	Tina Duong Tina Duong Kristin J. Krosschell Meredith K. James Leslie Nelson Lindsay N. Alfano Lindsay N. Alfano Katy Eichinger Elena Mazzone Kristy Rose Linda P. Lowes Linda P. Lowes Anna Mayhew Julaine Florence Wendy King Claudia R. Senesac Michelle Eagle Michelle Eagle
author_sort	Tina Duong
title	Consensus Guidelines for Improving Quality of Assessment and Training for Neuromuscular Diseases
title_short	Consensus Guidelines for Improving Quality of Assessment and Training for Neuromuscular Diseases
title_full	Consensus Guidelines for Improving Quality of Assessment and Training for Neuromuscular Diseases
title_fullStr	Consensus Guidelines for Improving Quality of Assessment and Training for Neuromuscular Diseases
title_full_unstemmed	Consensus Guidelines for Improving Quality of Assessment and Training for Neuromuscular Diseases
title_sort	consensus guidelines for improving quality of assessment and training for neuromuscular diseases
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/981e516b28d04a8384a87ee77f7b25aa
work_keys_str_mv	AT tinaduong consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT tinaduong consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT kristinjkrosschell consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT meredithkjames consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT leslienelson consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT lindsaynalfano consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT lindsaynalfano consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT katyeichinger consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT elenamazzone consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT kristyrose consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT lindaplowes consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT lindaplowes consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT annamayhew consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT julaineflorence consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT wendyking consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT claudiarsenesac consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT michelleeagle consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases AT michelleeagle consensusguidelinesforimprovingqualityofassessmentandtrainingforneuromusculardiseases
_version_	1718440400150069248

Consensus Guidelines for Improving Quality of Assessment and Training for Neuromuscular Diseases

Ejemplares similares