Age-related macular degeneration

Giuseppe Querques¹, Fernando Onofrio Avellis1,2, Lea Querques1,3, Francesco Bandello³, Eric H Souied¹ ¹Service d'Ophtalmologie, Centre Hospitalier Intercommunal Créteil, Université Paris-Est Cr&eacu...

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Autores principales: Querques G, Avellis FO, Querques L, Bandello F, Souied EH
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Publicado: Dove Medical Press 2011
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Acceso en línea:https://doaj.org/article/98282558f61948969cb097a903428cee
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spelling oai:doaj.org-article:98282558f61948969cb097a903428cee2021-12-02T01:52:04ZAge-related macular degeneration1177-54671177-5483https://doaj.org/article/98282558f61948969cb097a903428cee2011-05-01T00:00:00Zhttp://www.dovepress.com/age-related-macular-degeneration-a7484https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Giuseppe Querques¹, Fernando Onofrio Avellis1,2, Lea Querques1,3, Francesco Bandello³, Eric H Souied¹ ¹Service d'Ophtalmologie, Centre Hospitalier Intercommunal Créteil, Université Paris-Est Créteil, Créteil, France; ²Parma Eye Clinic University Hospital, Università degli Studi di Parma, Parma, Italy; ³Department of Ophthalmology, Università Vita-Salute San Raffaele Milano, Milano, Italy Date of preparation: March 3, 2011 Conflict of interest: None declaredClinical question: Is there any new knowledge about the pathogenesis and treatment of age-related macular degeneration (AMD)?Results: We now understand better the biochemical and pathological pathways involved in the genesis of AMD. Treatment of exudative AMD is based on intravitreal injection of new antivascular endothelial growth factor drugs for which there does not yet exist a unique recognized strategy of administration. No therapies are actually available for atrophic AMD, despite some experimental new pharmacological approaches.Implementation: strategy of administration, safety of intravitreal injectionKeywords: age-related macular degeneration, antivascular endothelial growth factor, choroidal neovascularization, drusen, geographic atrophyQuerques GAvellis FOQuerques LBandello FSouied EHDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 593-601 (2011)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Querques G
Avellis FO
Querques L
Bandello F
Souied EH
Age-related macular degeneration
description Giuseppe Querques¹, Fernando Onofrio Avellis1,2, Lea Querques1,3, Francesco Bandello³, Eric H Souied¹ ¹Service d'Ophtalmologie, Centre Hospitalier Intercommunal Créteil, Université Paris-Est Créteil, Créteil, France; ²Parma Eye Clinic University Hospital, Università degli Studi di Parma, Parma, Italy; ³Department of Ophthalmology, Università Vita-Salute San Raffaele Milano, Milano, Italy Date of preparation: March 3, 2011 Conflict of interest: None declaredClinical question: Is there any new knowledge about the pathogenesis and treatment of age-related macular degeneration (AMD)?Results: We now understand better the biochemical and pathological pathways involved in the genesis of AMD. Treatment of exudative AMD is based on intravitreal injection of new antivascular endothelial growth factor drugs for which there does not yet exist a unique recognized strategy of administration. No therapies are actually available for atrophic AMD, despite some experimental new pharmacological approaches.Implementation: strategy of administration, safety of intravitreal injectionKeywords: age-related macular degeneration, antivascular endothelial growth factor, choroidal neovascularization, drusen, geographic atrophy
format article
author Querques G
Avellis FO
Querques L
Bandello F
Souied EH
author_facet Querques G
Avellis FO
Querques L
Bandello F
Souied EH
author_sort Querques G
title Age-related macular degeneration
title_short Age-related macular degeneration
title_full Age-related macular degeneration
title_fullStr Age-related macular degeneration
title_full_unstemmed Age-related macular degeneration
title_sort age-related macular degeneration
publisher Dove Medical Press
publishDate 2011
url https://doaj.org/article/98282558f61948969cb097a903428cee
work_keys_str_mv AT querquesg agerelatedmaculardegeneration
AT avellisfo agerelatedmaculardegeneration
AT querquesl agerelatedmaculardegeneration
AT bandellof agerelatedmaculardegeneration
AT souiedeh agerelatedmaculardegeneration
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