Low frequency of local findings in periprosthetic hip infection caused by low-virulent bacteria compared to periprosthetic knee infection

Abstract Periprosthetic joint infection (PJI) is suspected when local findings such as pain, swelling, hyperthermia, and sinus tract are present. However, the frequency of these findings and the difference between hip and knee are unclear. This study compared the positive rates of local findings in...

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Autores principales:	Takashi Imagama, Kazushige Seki, Toshihiro Seki, Yuta Matsuki, Kazuhiro Yamazaki, Takashi Sakai
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/982fd542f64946259a094b6283fba749
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spelling	oai:doaj.org-article:982fd542f64946259a094b6283fba7492021-12-02T15:02:40ZLow frequency of local findings in periprosthetic hip infection caused by low-virulent bacteria compared to periprosthetic knee infection10.1038/s41598-021-91139-w2045-2322https://doaj.org/article/982fd542f64946259a094b6283fba7492021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-91139-whttps://doaj.org/toc/2045-2322Abstract Periprosthetic joint infection (PJI) is suspected when local findings such as pain, swelling, hyperthermia, and sinus tract are present. However, the frequency of these findings and the difference between hip and knee are unclear. This study compared the positive rates of local findings in periprosthetic hip infection (PHI) with periprosthetic knee infection (PKI), and aimed to identify potential risk factors associated with the frequency. One hundred one PJI (46 hips and 55 knees) fulfilled the 2018 Musculoskeletal infection society criteria were analysed retrospectively to assess the positive rates of each local finding. Patients were categorized into two groups based on the presence or absence of each local finding, and the influence of two potential risk factors [body mass index (BMI) and C-reactive protein (CRP)] was investigated. Causative bacterial species were divided into high and low-virulent groups, and then culture negative cases were included in low-virulent group. PHI had significantly lower rates of pain, swelling and hyperthermia compared to PKI. Overall, up to one-third of PHI had pain as only symptom. High BMI and low-virulent bacteria were associated with lower frequency of swelling and hyperthermia in PHI. CRP had no impact on positive rates of local findings. PHI was oligosymptomatic in a significant percentage of cases. This is particularly important in obese patients and infection by low-virulent bacteria.Takashi ImagamaKazushige SekiToshihiro SekiYuta MatsukiKazuhiro YamazakiTakashi SakaiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Takashi Imagama Kazushige Seki Toshihiro Seki Yuta Matsuki Kazuhiro Yamazaki Takashi Sakai Low frequency of local findings in periprosthetic hip infection caused by low-virulent bacteria compared to periprosthetic knee infection
description	Abstract Periprosthetic joint infection (PJI) is suspected when local findings such as pain, swelling, hyperthermia, and sinus tract are present. However, the frequency of these findings and the difference between hip and knee are unclear. This study compared the positive rates of local findings in periprosthetic hip infection (PHI) with periprosthetic knee infection (PKI), and aimed to identify potential risk factors associated with the frequency. One hundred one PJI (46 hips and 55 knees) fulfilled the 2018 Musculoskeletal infection society criteria were analysed retrospectively to assess the positive rates of each local finding. Patients were categorized into two groups based on the presence or absence of each local finding, and the influence of two potential risk factors [body mass index (BMI) and C-reactive protein (CRP)] was investigated. Causative bacterial species were divided into high and low-virulent groups, and then culture negative cases were included in low-virulent group. PHI had significantly lower rates of pain, swelling and hyperthermia compared to PKI. Overall, up to one-third of PHI had pain as only symptom. High BMI and low-virulent bacteria were associated with lower frequency of swelling and hyperthermia in PHI. CRP had no impact on positive rates of local findings. PHI was oligosymptomatic in a significant percentage of cases. This is particularly important in obese patients and infection by low-virulent bacteria.
format	article
author	Takashi Imagama Kazushige Seki Toshihiro Seki Yuta Matsuki Kazuhiro Yamazaki Takashi Sakai
author_facet	Takashi Imagama Kazushige Seki Toshihiro Seki Yuta Matsuki Kazuhiro Yamazaki Takashi Sakai
author_sort	Takashi Imagama
title	Low frequency of local findings in periprosthetic hip infection caused by low-virulent bacteria compared to periprosthetic knee infection
title_short	Low frequency of local findings in periprosthetic hip infection caused by low-virulent bacteria compared to periprosthetic knee infection
title_full	Low frequency of local findings in periprosthetic hip infection caused by low-virulent bacteria compared to periprosthetic knee infection
title_fullStr	Low frequency of local findings in periprosthetic hip infection caused by low-virulent bacteria compared to periprosthetic knee infection
title_full_unstemmed	Low frequency of local findings in periprosthetic hip infection caused by low-virulent bacteria compared to periprosthetic knee infection
title_sort	low frequency of local findings in periprosthetic hip infection caused by low-virulent bacteria compared to periprosthetic knee infection
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/982fd542f64946259a094b6283fba749
work_keys_str_mv	AT takashiimagama lowfrequencyoflocalfindingsinperiprosthetichipinfectioncausedbylowvirulentbacteriacomparedtoperiprosthetickneeinfection AT kazushigeseki lowfrequencyoflocalfindingsinperiprosthetichipinfectioncausedbylowvirulentbacteriacomparedtoperiprosthetickneeinfection AT toshihiroseki lowfrequencyoflocalfindingsinperiprosthetichipinfectioncausedbylowvirulentbacteriacomparedtoperiprosthetickneeinfection AT yutamatsuki lowfrequencyoflocalfindingsinperiprosthetichipinfectioncausedbylowvirulentbacteriacomparedtoperiprosthetickneeinfection AT kazuhiroyamazaki lowfrequencyoflocalfindingsinperiprosthetichipinfectioncausedbylowvirulentbacteriacomparedtoperiprosthetickneeinfection AT takashisakai lowfrequencyoflocalfindingsinperiprosthetichipinfectioncausedbylowvirulentbacteriacomparedtoperiprosthetickneeinfection
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Low frequency of local findings in periprosthetic hip infection caused by low-virulent bacteria compared to periprosthetic knee infection

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