Huge Pulmonary Sclerosing Pneumocytoma with Endobronchial Invasion: A Case Report with a Literature Review

Pulmonary sclerosing pneumocytoma (PSP) is a tumor of pneumocytic origin that is classified as a benign neoplasm. To date, aggressive behavior of this tumor has rarely been reported. Here, we describe a case of a 56-year-old woman with a huge, 19-cm PSP that resulted in mediastinal shift and show...

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Autores principales: Hyun Soo Lee, Jina Kim, Duk Hwan Moon, Chul Hwan Park, Tae Joo Jeon, Sungsoo Lee, Yoon Jin Cha
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Lenguaje:EN
Publicado: Korean Society for Thoracic & Cardiovascular Surgery 2021
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Acceso en línea:https://doaj.org/article/9831716302924de99422505319700537
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spelling oai:doaj.org-article:9831716302924de994225053197005372021-12-03T01:51:22ZHuge Pulmonary Sclerosing Pneumocytoma with Endobronchial Invasion: A Case Report with a Literature Review10.5090/jcs.21.0162765-16062765-1614https://doaj.org/article/9831716302924de994225053197005372021-12-01T00:00:00Zhttps://doaj.org/toc/2765-1606https://doaj.org/toc/2765-1614Pulmonary sclerosing pneumocytoma (PSP) is a tumor of pneumocytic origin that is classified as a benign neoplasm. To date, aggressive behavior of this tumor has rarely been reported. Here, we describe a case of a 56-year-old woman with a huge, 19-cm PSP that resulted in mediastinal shift and showed microscopic endobronchial invasion and necrosis. The differential diagnosis included malignant mesenchymal tumors, such as solitary fibrous tumor; however, PSP was confirmed based on the characteristic thyroid transcription factor 1 positivity and membranous expression of Ki-67 on immunohistochemical staining of tumor cells.Hyun Soo LeeJina KimDuk Hwan MoonChul Hwan ParkTae Joo JeonSungsoo LeeYoon Jin ChaKorean Society for Thoracic & Cardiovascular Surgeryarticlepulmonary sclerosing hemangiomacomputed tomographyimmunohistochemistrycase reportMedicine (General)R5-920ENJournal of Chest Surgery, Vol 54, Iss 6, Pp 528-531 (2021)
institution DOAJ
collection DOAJ
language EN
topic pulmonary sclerosing hemangioma
computed tomography
immunohistochemistry
case report
Medicine (General)
R5-920
spellingShingle pulmonary sclerosing hemangioma
computed tomography
immunohistochemistry
case report
Medicine (General)
R5-920
Hyun Soo Lee
Jina Kim
Duk Hwan Moon
Chul Hwan Park
Tae Joo Jeon
Sungsoo Lee
Yoon Jin Cha
Huge Pulmonary Sclerosing Pneumocytoma with Endobronchial Invasion: A Case Report with a Literature Review
description Pulmonary sclerosing pneumocytoma (PSP) is a tumor of pneumocytic origin that is classified as a benign neoplasm. To date, aggressive behavior of this tumor has rarely been reported. Here, we describe a case of a 56-year-old woman with a huge, 19-cm PSP that resulted in mediastinal shift and showed microscopic endobronchial invasion and necrosis. The differential diagnosis included malignant mesenchymal tumors, such as solitary fibrous tumor; however, PSP was confirmed based on the characteristic thyroid transcription factor 1 positivity and membranous expression of Ki-67 on immunohistochemical staining of tumor cells.
format article
author Hyun Soo Lee
Jina Kim
Duk Hwan Moon
Chul Hwan Park
Tae Joo Jeon
Sungsoo Lee
Yoon Jin Cha
author_facet Hyun Soo Lee
Jina Kim
Duk Hwan Moon
Chul Hwan Park
Tae Joo Jeon
Sungsoo Lee
Yoon Jin Cha
author_sort Hyun Soo Lee
title Huge Pulmonary Sclerosing Pneumocytoma with Endobronchial Invasion: A Case Report with a Literature Review
title_short Huge Pulmonary Sclerosing Pneumocytoma with Endobronchial Invasion: A Case Report with a Literature Review
title_full Huge Pulmonary Sclerosing Pneumocytoma with Endobronchial Invasion: A Case Report with a Literature Review
title_fullStr Huge Pulmonary Sclerosing Pneumocytoma with Endobronchial Invasion: A Case Report with a Literature Review
title_full_unstemmed Huge Pulmonary Sclerosing Pneumocytoma with Endobronchial Invasion: A Case Report with a Literature Review
title_sort huge pulmonary sclerosing pneumocytoma with endobronchial invasion: a case report with a literature review
publisher Korean Society for Thoracic & Cardiovascular Surgery
publishDate 2021
url https://doaj.org/article/9831716302924de99422505319700537
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