Social cognition in neuropsychiatric populations: a comparison of theory of mind in schizophrenia and mesial temporal lobe epilepsy

Abstract Social cognition deficits are observed both in patients with schizophrenia (SCZ) and in patients with mesial temporal lobe epilepsy (MTLE). This may be due to dysfunction of the amygdala network, which is a common feature of both diseases. In this study, SCZ (n = 48) or MTLE (n = 31) and he...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Łukasz Okruszek, Aleksandra Bala, Małgorzata Wordecha, Michał Jarkiewicz, Adam Wysokiński, Ewa Szczepocka, Aleksandra Piejka, Oliwia Zaborowska, Marta Szantroch, Andrzej Rysz, Andrzej Marchel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/98352e2bc9674a20acd72b4ba19022bb
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:98352e2bc9674a20acd72b4ba19022bb
record_format	dspace
spelling	oai:doaj.org-article:98352e2bc9674a20acd72b4ba19022bb2021-12-02T16:06:06ZSocial cognition in neuropsychiatric populations: a comparison of theory of mind in schizophrenia and mesial temporal lobe epilepsy10.1038/s41598-017-00565-22045-2322https://doaj.org/article/98352e2bc9674a20acd72b4ba19022bb2017-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-00565-2https://doaj.org/toc/2045-2322Abstract Social cognition deficits are observed both in patients with schizophrenia (SCZ) and in patients with mesial temporal lobe epilepsy (MTLE). This may be due to dysfunction of the amygdala network, which is a common feature of both diseases. In this study, SCZ (n = 48) or MTLE (n = 31) and healthy controls (HC, n = 47) completed assessments of mentalising (Reading Mind in the Eyes Test, RMET) and basic cognitive processing, e.g., working memory, executive functions and psychomotor speed (Trail-Making Test B and Digit Symbol). SCZ were also assessed with the Positive And Negative Syndrome Scale (PANSS). We found that the RMET scores of the two clinical groups were similar (p > 0.05) and lower than in the HCs (SCZ: p < 0.05; MTLE: p < 0.001). In the next step, SCZ were split into two groups with respect to the level of symptoms. Analysis of the RMET scores revealed no differences between the HC (M = 25.7 ± 4.1) and POS-LO (M = 25.3 ± 4.8); both groups outperformed the POS-HI group (M = 21.3 ± 5.2) and the MTLE group (M = 20.8 ± 4.6). No differences were found for the median-split with regard to negative symptoms. In SCZ, the mind-reading deficit appears to be associated with the level of positive symptoms. Both POS-HI and MTLE patients present significant mentalising deficits compared to healthy controls.Łukasz OkruszekAleksandra BalaMałgorzata WordechaMichał JarkiewiczAdam WysokińskiEwa SzczepockaAleksandra PiejkaOliwia ZaborowskaMarta SzantrochAndrzej RyszAndrzej MarchelNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Łukasz Okruszek Aleksandra Bala Małgorzata Wordecha Michał Jarkiewicz Adam Wysokiński Ewa Szczepocka Aleksandra Piejka Oliwia Zaborowska Marta Szantroch Andrzej Rysz Andrzej Marchel Social cognition in neuropsychiatric populations: a comparison of theory of mind in schizophrenia and mesial temporal lobe epilepsy
description	Abstract Social cognition deficits are observed both in patients with schizophrenia (SCZ) and in patients with mesial temporal lobe epilepsy (MTLE). This may be due to dysfunction of the amygdala network, which is a common feature of both diseases. In this study, SCZ (n = 48) or MTLE (n = 31) and healthy controls (HC, n = 47) completed assessments of mentalising (Reading Mind in the Eyes Test, RMET) and basic cognitive processing, e.g., working memory, executive functions and psychomotor speed (Trail-Making Test B and Digit Symbol). SCZ were also assessed with the Positive And Negative Syndrome Scale (PANSS). We found that the RMET scores of the two clinical groups were similar (p > 0.05) and lower than in the HCs (SCZ: p < 0.05; MTLE: p < 0.001). In the next step, SCZ were split into two groups with respect to the level of symptoms. Analysis of the RMET scores revealed no differences between the HC (M = 25.7 ± 4.1) and POS-LO (M = 25.3 ± 4.8); both groups outperformed the POS-HI group (M = 21.3 ± 5.2) and the MTLE group (M = 20.8 ± 4.6). No differences were found for the median-split with regard to negative symptoms. In SCZ, the mind-reading deficit appears to be associated with the level of positive symptoms. Both POS-HI and MTLE patients present significant mentalising deficits compared to healthy controls.
format	article
author	Łukasz Okruszek Aleksandra Bala Małgorzata Wordecha Michał Jarkiewicz Adam Wysokiński Ewa Szczepocka Aleksandra Piejka Oliwia Zaborowska Marta Szantroch Andrzej Rysz Andrzej Marchel
author_facet	Łukasz Okruszek Aleksandra Bala Małgorzata Wordecha Michał Jarkiewicz Adam Wysokiński Ewa Szczepocka Aleksandra Piejka Oliwia Zaborowska Marta Szantroch Andrzej Rysz Andrzej Marchel
author_sort	Łukasz Okruszek
title	Social cognition in neuropsychiatric populations: a comparison of theory of mind in schizophrenia and mesial temporal lobe epilepsy
title_short	Social cognition in neuropsychiatric populations: a comparison of theory of mind in schizophrenia and mesial temporal lobe epilepsy
title_full	Social cognition in neuropsychiatric populations: a comparison of theory of mind in schizophrenia and mesial temporal lobe epilepsy
title_fullStr	Social cognition in neuropsychiatric populations: a comparison of theory of mind in schizophrenia and mesial temporal lobe epilepsy
title_full_unstemmed	Social cognition in neuropsychiatric populations: a comparison of theory of mind in schizophrenia and mesial temporal lobe epilepsy
title_sort	social cognition in neuropsychiatric populations: a comparison of theory of mind in schizophrenia and mesial temporal lobe epilepsy
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/98352e2bc9674a20acd72b4ba19022bb
work_keys_str_mv	AT łukaszokruszek socialcognitioninneuropsychiatricpopulationsacomparisonoftheoryofmindinschizophreniaandmesialtemporallobeepilepsy AT aleksandrabala socialcognitioninneuropsychiatricpopulationsacomparisonoftheoryofmindinschizophreniaandmesialtemporallobeepilepsy AT małgorzatawordecha socialcognitioninneuropsychiatricpopulationsacomparisonoftheoryofmindinschizophreniaandmesialtemporallobeepilepsy AT michałjarkiewicz socialcognitioninneuropsychiatricpopulationsacomparisonoftheoryofmindinschizophreniaandmesialtemporallobeepilepsy AT adamwysokinski socialcognitioninneuropsychiatricpopulationsacomparisonoftheoryofmindinschizophreniaandmesialtemporallobeepilepsy AT ewaszczepocka socialcognitioninneuropsychiatricpopulationsacomparisonoftheoryofmindinschizophreniaandmesialtemporallobeepilepsy AT aleksandrapiejka socialcognitioninneuropsychiatricpopulationsacomparisonoftheoryofmindinschizophreniaandmesialtemporallobeepilepsy AT oliwiazaborowska socialcognitioninneuropsychiatricpopulationsacomparisonoftheoryofmindinschizophreniaandmesialtemporallobeepilepsy AT martaszantroch socialcognitioninneuropsychiatricpopulationsacomparisonoftheoryofmindinschizophreniaandmesialtemporallobeepilepsy AT andrzejrysz socialcognitioninneuropsychiatricpopulationsacomparisonoftheoryofmindinschizophreniaandmesialtemporallobeepilepsy AT andrzejmarchel socialcognitioninneuropsychiatricpopulationsacomparisonoftheoryofmindinschizophreniaandmesialtemporallobeepilepsy
_version_	1718385104489807872

Social cognition in neuropsychiatric populations: a comparison of theory of mind in schizophrenia and mesial temporal lobe epilepsy

Ejemplares similares