Is high myopia a risk factor for visual field progression or disk hemorrhage in primary open-angle glaucoma?

Koji Nitta,1 Kazuhisa Sugiyama,2 Ryotaro Wajima,1 Gaku Tachibana1 1Department of Ophthalmology, Fukui-ken Saiseikai Hospital, Fukui, 2Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan Purpose: The purpose of this study was to clarify differences b...

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Autores principales:	Nitta K, Sugiyama K, Wajima R, Tachibana G
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	myopic glaucoma disc hemorrhage open angle glaucoma visual field defect progression high myopia Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/983772e9bdde47b5a182c9bceff0a40b
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spelling	oai:doaj.org-article:983772e9bdde47b5a182c9bceff0a40b2021-12-02T04:50:42ZIs high myopia a risk factor for visual field progression or disk hemorrhage in primary open-angle glaucoma?1177-5483https://doaj.org/article/983772e9bdde47b5a182c9bceff0a40b2017-04-01T00:00:00Zhttps://www.dovepress.com/is-high-myopia-a-risk-factor-for-visual-field-progression-or-disk--hem-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Koji Nitta,1 Kazuhisa Sugiyama,2 Ryotaro Wajima,1 Gaku Tachibana1 1Department of Ophthalmology, Fukui-ken Saiseikai Hospital, Fukui, 2Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan Purpose: The purpose of this study was to clarify differences between highly myopic and non-myopic primary open-angle glaucoma (POAG) patients, including normal-tension glaucoma patients.Patients and methods: A total of 269 POAG patients were divided into two groups: patients with ≥26.5 mm of axial length (highly myopic group) and patients with <24.0 mm of axial length (non-myopic group).Results: We analyzed 53 highly myopic and 93 non-myopic POAG patients. Age at first visit of the highly myopic group was significantly less than that of the non-myopic group (P<0.0001). Baseline intraocular pressures (IOPs) showed no significant differences. Follow-up IOPs of the non-myopic group were significantly lower than those of the highly myopic group (P=0.0009). According to the mean deviation definition of progression, the cumulative probability of non-progression of visual field (VF) loss was significantly greater in the highly myopic group (10-year survival rate, 73.7%±6.8%) than in the non-myopic group (10-year survival rate, 46.3%±5.8%; log-rank test, P=0.0142). The occurrence of disk hemorrhage (DH) in the non-myopic group (1.60±3.04) was significantly greater than that in the highly myopic group (0.93±2.13, P=0.0311). The cumulative probability of DH was significantly lower in the highly myopic group (10-year survival rate, 26.4%±5.4%) than in the non-myopic group (10-year survival rate, 47.2%±6.6%, P=0.0413).Conclusion: Highly myopic POAG is considered as a combination of myopic optic neuropathy and glaucomatous optic neuropathy (GON). If GON is predominant, it has frequent DH and more progressive VF loss. However, when the myopic optic neuropathy is predominant, it has less DH and less progressive VF loss. Keywords: myopic glaucoma, disk hemorrhage, open-angle glaucoma, visual field defect progression, high myopia Nitta KSugiyama KWajima RTachibana GDove Medical Pressarticlemyopic glaucomadisc hemorrhageopen angle glaucomavisual field defect progressionhigh myopiaOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 11, Pp 599-604 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	myopic glaucoma disc hemorrhage open angle glaucoma visual field defect progression high myopia Ophthalmology RE1-994
spellingShingle	myopic glaucoma disc hemorrhage open angle glaucoma visual field defect progression high myopia Ophthalmology RE1-994 Nitta K Sugiyama K Wajima R Tachibana G Is high myopia a risk factor for visual field progression or disk hemorrhage in primary open-angle glaucoma?
description	Koji Nitta,1 Kazuhisa Sugiyama,2 Ryotaro Wajima,1 Gaku Tachibana1 1Department of Ophthalmology, Fukui-ken Saiseikai Hospital, Fukui, 2Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan Purpose: The purpose of this study was to clarify differences between highly myopic and non-myopic primary open-angle glaucoma (POAG) patients, including normal-tension glaucoma patients.Patients and methods: A total of 269 POAG patients were divided into two groups: patients with ≥26.5 mm of axial length (highly myopic group) and patients with <24.0 mm of axial length (non-myopic group).Results: We analyzed 53 highly myopic and 93 non-myopic POAG patients. Age at first visit of the highly myopic group was significantly less than that of the non-myopic group (P<0.0001). Baseline intraocular pressures (IOPs) showed no significant differences. Follow-up IOPs of the non-myopic group were significantly lower than those of the highly myopic group (P=0.0009). According to the mean deviation definition of progression, the cumulative probability of non-progression of visual field (VF) loss was significantly greater in the highly myopic group (10-year survival rate, 73.7%±6.8%) than in the non-myopic group (10-year survival rate, 46.3%±5.8%; log-rank test, P=0.0142). The occurrence of disk hemorrhage (DH) in the non-myopic group (1.60±3.04) was significantly greater than that in the highly myopic group (0.93±2.13, P=0.0311). The cumulative probability of DH was significantly lower in the highly myopic group (10-year survival rate, 26.4%±5.4%) than in the non-myopic group (10-year survival rate, 47.2%±6.6%, P=0.0413).Conclusion: Highly myopic POAG is considered as a combination of myopic optic neuropathy and glaucomatous optic neuropathy (GON). If GON is predominant, it has frequent DH and more progressive VF loss. However, when the myopic optic neuropathy is predominant, it has less DH and less progressive VF loss. Keywords: myopic glaucoma, disk hemorrhage, open-angle glaucoma, visual field defect progression, high myopia
format	article
author	Nitta K Sugiyama K Wajima R Tachibana G
author_facet	Nitta K Sugiyama K Wajima R Tachibana G
author_sort	Nitta K
title	Is high myopia a risk factor for visual field progression or disk hemorrhage in primary open-angle glaucoma?
title_short	Is high myopia a risk factor for visual field progression or disk hemorrhage in primary open-angle glaucoma?
title_full	Is high myopia a risk factor for visual field progression or disk hemorrhage in primary open-angle glaucoma?
title_fullStr	Is high myopia a risk factor for visual field progression or disk hemorrhage in primary open-angle glaucoma?
title_full_unstemmed	Is high myopia a risk factor for visual field progression or disk hemorrhage in primary open-angle glaucoma?
title_sort	is high myopia a risk factor for visual field progression or disk hemorrhage in primary open-angle glaucoma?
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/983772e9bdde47b5a182c9bceff0a40b
work_keys_str_mv	AT nittak ishighmyopiaariskfactorforvisualfieldprogressionordiskhemorrhageinprimaryopenangleglaucoma AT sugiyamak ishighmyopiaariskfactorforvisualfieldprogressionordiskhemorrhageinprimaryopenangleglaucoma AT wajimar ishighmyopiaariskfactorforvisualfieldprogressionordiskhemorrhageinprimaryopenangleglaucoma AT tachibanag ishighmyopiaariskfactorforvisualfieldprogressionordiskhemorrhageinprimaryopenangleglaucoma
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Is high myopia a risk factor for visual field progression or disk hemorrhage in primary open-angle glaucoma?

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