Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA

The transcription co-activator complex SAGA is recruited to promoters by transcriptional activators and promotes the formation of the pre-initiation complex. Here, the authors present the cryo-EM structure of the SAGA complex and resolve the major target of activator binding, the 430 kDa Tra1 protei...

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Autores principales:	Grigory Sharov, Karine Voltz, Alexandre Durand, Olga Kolesnikova, Gabor Papai, Alexander G. Myasnikov, Annick Dejaegere, Adam Ben Shem, Patrick Schultz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9840b937571446d3924b256fc336f3ee
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spelling	oai:doaj.org-article:9840b937571446d3924b256fc336f3ee2021-12-02T17:06:25ZStructure of the transcription activator target Tra1 within the chromatin modifying complex SAGA10.1038/s41467-017-01564-72041-1723https://doaj.org/article/9840b937571446d3924b256fc336f3ee2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01564-7https://doaj.org/toc/2041-1723The transcription co-activator complex SAGA is recruited to promoters by transcriptional activators and promotes the formation of the pre-initiation complex. Here, the authors present the cryo-EM structure of the SAGA complex and resolve the major target of activator binding, the 430 kDa Tra1 protein.Grigory SharovKarine VoltzAlexandre DurandOlga KolesnikovaGabor PapaiAlexander G. MyasnikovAnnick DejaegereAdam Ben ShemPatrick SchultzNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Grigory Sharov Karine Voltz Alexandre Durand Olga Kolesnikova Gabor Papai Alexander G. Myasnikov Annick Dejaegere Adam Ben Shem Patrick Schultz Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA
description	The transcription co-activator complex SAGA is recruited to promoters by transcriptional activators and promotes the formation of the pre-initiation complex. Here, the authors present the cryo-EM structure of the SAGA complex and resolve the major target of activator binding, the 430 kDa Tra1 protein.
format	article
author	Grigory Sharov Karine Voltz Alexandre Durand Olga Kolesnikova Gabor Papai Alexander G. Myasnikov Annick Dejaegere Adam Ben Shem Patrick Schultz
author_facet	Grigory Sharov Karine Voltz Alexandre Durand Olga Kolesnikova Gabor Papai Alexander G. Myasnikov Annick Dejaegere Adam Ben Shem Patrick Schultz
author_sort	Grigory Sharov
title	Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA
title_short	Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA
title_full	Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA
title_fullStr	Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA
title_full_unstemmed	Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA
title_sort	structure of the transcription activator target tra1 within the chromatin modifying complex saga
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/9840b937571446d3924b256fc336f3ee
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Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA

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